High and Low Salt Intake during Pregnancy: Impact on Cardiac and Renal Structure in Newborns.

Introduction: Previous studies from our laboratory demonstrated that dietary salt overload and salt restriction during pregnancy were associated with cardiac and renal structural and/or functional alterations in adult offspring. The present study evaluated renal and cardiac structure and the local renin-angiotensin system in newborns from dams fed high-, normal- or low-salt diets during pregnancy.

Methods: Female Wistar rats were fed low- (LS, 0.