Publications by authors named "Breno C Landim"

Article Synopsis
  • The study investigated the effects of a hydroalcoholic extract from plant leaves on skin wound healing by testing it on mice with induced wounds over a period of 7 days.
  • The extract notably improved wound closure, showing significant anti-inflammatory properties and increased collagen levels, particularly at a 4% concentration.
  • The presence of phenolic compounds and tannins in the extract was linked to its healing effects, suggesting that standardized plant extracts could be a promising treatment for wound management.
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Recent studies have been trying to find out how diet and metabolic changes such as dyslipidaemia, hyperglycaemia, and hyperinsulinaemia can stimulate cancer progression. This investigation aimed to evaluate the effect of high concentrations of fatty acids and/or glucose in tumour prostate cells, focusing on the proliferation/migration profile and oxidative stress. PC3 cells were treated with high concentration of saturated fatty acid (palmitate, 100 µM), glucose (220 mg/dL), or both for 24 or 48 h.

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Background: A potential association between obesity and prostate cancer has been proposed. Metformin, an antidiabetes drug, has antiproliferative effects being proposed for cancer treatment. However, under intense proliferative stimulation conditions such as those found in obesity, its efficacy is still uncertain.

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