Contribution of scintigraphy and ultrasonography to the prediction of malignancy in thyroid nodules with indeterminate cytology.

Objective: To evaluate the contribution of (131)I scintigraphy and ultrasonography to the prediction of malignancy in thyroid nodules with indeterminate cytology in euthyroid patients.

Subjects And Methods: The sample consisted of 102 patients with thyroid nodules, submitted to FNAC and presenting an indeterminate cytological diagnosis (follicular neoplasm).

Results: Malignancy was observed in 19/25 (76%) nodules with suspicious ultrasonographic characteristics versus 5/77 (6.

Low false-negative rate of cytology in thyroid nodules >or= 4 cm.

Objective: To report the results of cytology and histology obtained for a series of systematically resected thyroid nodules >or= 4 cm.

Methods: A group of 151 patients with thyroid nodules >or= 4 cm was submitted to surgery despite the cytology result.

Results: Malignancy was confirmed histologically in 22.

Natural history of mild subclinical hypothyroidism: prognostic value of ultrasound.

Background: Clinical repercussions, progression to overt hypothyroidism, and treatment benefits have been well established in patients with subclinical hypothyroidism (SCH) and TSH >10 mIU/L. In contrast, these aspects of the disease are poorly understood in patients with even milder SCH as defined by TSH < or = 10 mIU/L and normal thyroid hormone levels. Therefore, we sought to evaluate the natural history of this milder form of SCH (TSH < or =10 mIU/L with normal thyroid hormone levels) in adult women patients.