Publications by authors named "Brennan Flannery"

Objective: To test if our artificial intelligence (AI)-postoperative glomerular filtration rate (GFR) prediction is as accurate as a validated clinical model. The American Urologic Association recommends estimating postoperative GFR in patients with renal masses and prioritizing partial nephrectomy (PN) when GFR would be <45 ml/minutes/1.73 m if radical nephrectomy (RN) was performed.

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Article Synopsis
  • Machine learning, particularly deep learning with convolutional neural networks (CNNs), is being used to detect prostate cancer in tissue slides, but sample type differences affect model accuracy.
  • Research tested whether CNNs trained on one type of sample (biopsy or radical prostatectomy) could effectively analyze the other type, revealing a significant drop in performance across sample types.
  • Results indicated that models performed well on their own sample but poorly on the alternative type, highlighting the need to consider morphological differences in training to improve cancer detection accuracy in clinical settings.*
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