Philos Trans A Math Phys Eng Sci
November 2023
Compound- and compound class-specific radiocarbon analysis of source-diagnostic 'biomarker' molecules has emerged as a powerful tool to gain insights into terrestrial carbon cycling. While most studies thus far have focused on higher plant biomarkers (i.e.
View Article and Find Full Text PDFThe relatively stable Holocene climate was preceded by a pronounced event of abrupt warming in the Northern Hemisphere, the termination of the Younger Dryas (YD) cold period. Although this transition has been intensively studied, its imprint on low-latitude ocean temperature is still controversial and its effects on sub-annual to decadal climate variability remain poorly understood. Sea surface temperature (SST) variability at these timescales in the tropical Atlantic is expected to intensify under current and future global warming and has considerable consequences for environmental conditions in Africa and South America, and for tropical Pacific climate.
View Article and Find Full Text PDFMicroorganisms produce a wide range of natural products (NPs) with clinically and agriculturally relevant biological activities. In bacteria and fungi, genes encoding successive steps in a biosynthetic pathway tend to be clustered on the chromosome as biosynthetic gene clusters (BGCs). Historically, "activity-guided" approaches to NP discovery have focused on bioactivity screening of NPs produced by culturable microbes.
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