Publications by authors named "Brendo V R Louredo"

Article Synopsis
  • The study analyzes the characteristics of oral reactions to injectable soft tissue fillers, focusing on 151 patients, predominantly females averaging 54.9 years old.
  • Most reactions occurred about 20.4 months after injection, often presenting as painless nodules in the lips, with silicone and polymethylmetacrylate being the most common fillers used.
  • Key findings showed differences in reaction patterns based on the type of filler and highlighted the importance for clinicians to recognize these potential reactions when assessing asymptomatic nodules in older female patients.
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Benign peripheral nerve sheath tumors (BPNSTs) are a vast, common, heterogeneous group of lesions that are often diagnostically challenging. The head and neck region is recognized as the second most common location for these lesions, especially the tongue. However, BPNSTs occurring centrally within the jaw bones are exceedingly rare.

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  • - A retrospective study was conducted to analyze 10 new cases of canalicular adenoma (CAD), reviewing medical records and histological slides from 2014-2024.
  • - The patients, primarily female with an average age of 61.2 years, presented mostly with solitary, asymptomatic nodules on the upper lip, and some experienced slight pain.
  • - The study emphasized distinct microscopic features of CAD and the utility of specific immunohistochemical markers in distinguishing CAD from other types of salivary gland tumors.
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  • The case involves a 76-year-old male who received multiple endodontic treatments for a misdiagnosed glandular odontogenic cyst, which was initially mistaken for an inflammatory periapical lesion.
  • Glandular odontogenic cysts are known to be more aggressive compared to other types, and there's a lack of extensive research on this in older dental patients.
  • The correct diagnosis was confirmed through a biopsy, leading to successful surgery while ensuring the base of the mandible was preserved, emphasizing the need for careful diagnosis in elderly patients.
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  • A case study of a 16-year-old girl with a four-year-old nodule on her tongue illustrates the tumor's characteristics, which included myxoid and chondroid features confirmed through surgical excision and histopathological analysis.
  • The tumor's immunohistochemical markers (GFAP and S-100 proteins) helped confirm the diagnosis, and after five years, the patient showed no signs of tumor recurrence, highlighting the importance of recognizing this distinctive tumor to prevent misdiagnosis.
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Purpose: This study describes a large, well-documented case series of salivary gland polymorphous adenocarcinomas (PAC) from a single Brazilian center.

Methods: Demographic data, clinical presentation, histopathological and immunohistochemical features from 26 cases of PAC were analyzed and discussed in detail.

Results: Most patients were females (n = 21), with a ratio of 1:4.

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Objective: This systematic review aimed to determine the clinical and epidemiologic profile of patients with burning mouth syndrome (BMS) following the current classification of the International Headache Society (IHS)-the International Classification of Headache Disorders (ICHD-3) and the International Classification of Orofacial Pain (ICOP).

Study Design: This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist and involved a comprehensive search on PubMed, Scopus, EMBASE, Web of Science, LILACS, and the gray literature.

Results: Of the 4,252 studies identified, 41 were included.

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This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients' histopathological records.

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The gingival cyst of the adult (GCA) is a rare odontogenic cyst, consisting of 0.3% of all odontogenic cysts. This case report, based on CARE guidelines for case reports, aims to present a case of a 52-year-old female patient with a symptomatic translucent nodule in the upper left anterior gingiva, measuring approximately 6mm.

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Objective: This systematic review aimed to describe the method followed during physical examination and the anatomical structures of the head and neck assessed in screening for oral cancer and oral potentially malignant disorders (OPMDs).

Study Design: An extensive literature search was carried out using MEDLINE/PubMed, EMBASE, Scopus, LILACS, Web of Science, Cochrane databases, and gray literature. The risk of bias was available in all papers included.

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Article Synopsis
  • Low-grade myofibroblastic sarcoma (LGMS) is a rare tumor typically found in the oral cavity and head/neck region, characterized by myofibroblast cells and a high chance of returning locally but low risk of spreading to distant sites.
  • The study analyzed 13 cases of LGMS from various countries, revealing that most patients are young females, often presenting with nodular lesions in the maxilla, and exhibiting specific microscopic and immunohistochemical features that confirm the diagnosis.
  • Complete surgical removal of the tumor is recommended for treatment, but additional long-term studies are needed to better understand recurrence rates and metastasis potential.
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  • The study aims to evaluate the effectiveness of cell block (CB) preparation from fine-needle aspiration cytology for diagnosing diseases in the oral and maxillofacial regions.
  • Over a period of 20 years, a retrospective analysis of 568 samples was conducted, comparing cytologic diagnoses with histopathologic diagnoses to assess accuracy and predictive values.
  • Results indicated that CB preparation showed a good overall accuracy of 80% and excellent specificity (100%) for identifying malignant lesions, suggesting it could be a valuable tool in diagnosing oral and maxillofacial diseases.
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  • DISR is a drug-induced condition resembling sarcoidosis, linked to certain medications, including TNF-α antagonists.
  • A case study of a 49-year-old woman with Crohn's Disease treated with adalimumab shows ulcerated swelling in the oral area, diagnosed with granulomas via biopsy.
  • It's important to recognize DISR in patients on anti-TNF-α therapy when evaluating oral granulomatous lesions to ensure proper diagnosis and management.
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Sialoblastoma is a rare malignant salivary gland tumor. The aim of this study was to review the available published data on sialoblastoma in a comprehensive analysis of its clinicopathologic characteristics, treatment, and outcomes. An unrestricted electronic search was performed in the following databases: MEDLINE/PubMed, EMBASE, Scopus, Web of science, and gray literature databases.

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Background: The available literature regarding metastasis to the oral cavity from colorectal cancer, especially rectal cancer, is currently limited. With this in mind, we aimed to report the first case of rectal adenocarcinoma metastasis to the oral vestibule.

Case Report: A 36-year-old Caucasian female with a 17-months history of rectal adenocarcinoma and several metastases was referred to the Dental Oncology Service due to a nodular swelling in the oral cavity.

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High-risk (HR) human papillomavirus (HPV) infection is recognized as a primary etiologic factor of anogenital cancers and more recently of a subgroup of oropharyngeal squamous cell carcinomas (OPSCC). The incidence of HPV-related OPSCC has increased dramatically in several developed countries in the past 3 decades and is currently the most common cancer caused by HR-HPV in the United States and Germany, surpassing cervical cancer. Consequently, the patient's demographic and clinicopathologic profile has shifted to nonsmoking and nondrinking younger men with higher schooling level and with a history of multiple oral sex partners.

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Background: To evaluate the frequency and analyze demographic and clinical characteristics of individuals with a histopathological diagnosis of oral lymphatic malformations (OLMs).

Methods: A multicenter study was performed, collecting biopsy record data from a consortium of Brazilian Oral and Maxillofacial Pathology Centers. A review was also conducted to compare this data with cases already available in the literature.

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Background: Salivary gland tumors are a diverse group of uncommon neoplasms that are rare in pediatric patients. The aim of this study was to evaluate the clinicopathological profile and survival outcomes of pediatric patients affected by salivary gland tumors.

Materials And Methods: An extensive search was carried out using the MEDLINE/PubMed, EMBASE, Scopus databases, and grey literature.

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Background: Analyze the clinical, demographic, histopathological, and immunohistochemical features of oral lymphoepithelial cyst (OLEC).

Methods: Samples were retrospectively retrieved from five oral pathology services. Clinical and demographic data were collected from patient charts.

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