Publications by authors named "Brendan Wesp"

Article Synopsis
  • - This study examined the relationship between clinical/demographic features and the intensity of treatments pediatric patients receive at the end of life (EOL), aiming to create a new classification system for these EOL trajectories.
  • - Conducted at a children's hospital from 2013 to 2021, the research included 1,111 patients aged 0-26, revealing that 85.7% died in-hospital, predominantly within ICUs.
  • - The analysis identified five key EOL trajectories, showing that certain patient characteristics, like recent surgeries or organ transplants, correlated with more aggressive treatments compared to those who had palliative care or were older.
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Context: The International Association for the Study of Pain (IASP) defines chronic pain as pain that persists or recurs for longer than 3 months. Chronic pain has a significant global disease burden with profound effects on health, quality of life, and socioeconomic costs.

Evidence Acquisition: Narrative review.

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Purpose Of Review: Loin pain hematuria syndrome (LPHS) is rare and seldom diagnosed, yet it has a particularly significant impact on those affected. This is a review of the latest and seminal evidence of the pathophysiology and diagnosis of LPHS and presents the typical clinical presentation and treatment options available.

Recent Findings: LPHS is typically found in young women with characteristic symptoms, including severe recurrent flank pain and gross or microscopic hematuria.

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Background: Necrotizing soft-tissue infections (NSTIs) result in significant morbidity and mortality rates, with as many as 76% of patients dying during their index admission. Published data suggest NSTIs rarely involve fungal infections in immunocompetent patients. However, because of the recent recognition of fungal infections in our population, we hypothesized that such infections frequently complicate NSTIs and are associated with higher morbidity and mortality rates.

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