Publications by authors named "Brendan Boland"

Pancreatic fistula (PF) continues to be the Achilles' heel of pancreaticoduodenectomy (PD) with both morbidity and mortality linked to its occurrence. The optimal drain management strategy after PD remains unclear. We evaluated drain amylase (DA) levels on postoperative Day (POD) 0 to 5 in 76 consecutive patients undergoing PD to determine the patterns associated with PF.

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Cholangiocarcinoma (CCA) continues to be a difficult disease to both diagnose and treat. Optimal treatment includes resection to histologically negative margins. In recent years, advanced imaging, including magnetic resonance cholangiography and endoscopic ultrasound, has presumably improved the accuracy of determining resectability.

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Background: Recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT) is rarely curable. However, in view of the advent of new treatments, it is critical that patients at high risk for recurrence are identified.

Methods: Patients undergoing LT for HCC at a single centre between 2002 and 2010 were reviewed and data on clinical parameters and explant pathology were analysed to determine factors associated with HCC recurrence.

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Infected pancreatic necrosis (IPN) continues to be a challenging problem for the surgeon. We reviewed the experience on a hepatobiliary surgical service with patients who required operative intervention for IPN with emphasis on surgical approach, timing of surgery, and complications. Between 2002 and 2008, 21 patients underwent surgery for IPN.

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Article Synopsis
  • Liver transplantation is a complex procedure, often complicated by bleeding and high blood pressure in the liver, particularly in Jehovah's Witness patients who cannot accept blood transfusions.
  • This study at the University of Southern California involved 10 liver transplants using recombinant human coagulation factor VIIa (rFVIIa) to manage bleeding, with all surgeries adhering to a transfusion-free protocol.
  • While most patients, especially those with live donor transplants, recovered well, two out of six cadaveric recipients unfortunately died due to complications linked to blood issues, suggesting the potential for rFVIIa's wider use in surgeries with similar bleeding challenges.
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