Publications by authors named "Brendan A S McIntyre"
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Synopsis of recent research by authors named "Brendan A S McIntyre"
- Brendan A S McIntyre's research primarily focuses on the differentiation and immune responses of stem cells, particularly in relation to airway epithelium and hematopoietic lineages, highlighting the potential of human pluripotent stem cells as a tool for therapeutic applications in regenerative medicine.
- His studies reveal novel techniques for isolating functionally active immune cells, such as eosinophils and neutrophils, as well as advancements in understanding the developmental programming and fate decisions in hematopoiesis, emphasizing the role of signaling pathways like Notch and Hedgehog.
- McIntyre also investigates genetic and cellular mechanisms underlying vascular malformations and pulmonary hypertension, contributing to a deeper understanding of how cellular processes impact developmental diseases and conditions with incomplete penetrance.
