Case Report: Characterization of known (c.607G>C) and novel (c.416C>G) mutations in two Mexican families with congenital neutropenia.

The most common causes of congenital neutropenia are mutations in the (Elastase, Neutrophil Expressed) gene (19p13.3), mostly in exon 5 and the distal portion of exon 4, which result in different clinical phenotypes of neutropenia. Here, we report two pathogenic mutations in , namely, c.

[Central venous-catheter related bacteremia: incidence and risk factors in a hospital in western México].

Background: Central venous catheters (CVC) are needed for monitoring and treatment of critically ill patients; however, their use increases the risk of bacteremia. The aim of the study was to quantify the incidence of central venous catheter-related bacteremia (CVCRB) and to identify factors associated with this infection.

Methods: A prospective cohort study was conducted in a concentration hospital of western Mexico.