Publications by authors named "Brenda Carrillo"
Background: Xylazine is a α2-adrenergic receptor agonist, used for sedation in veterinary contexts. Although it is increasingly found in overdose deaths across North America, the clinical management of xylazine-involved overdoses has not been extensively studied, especially in community-based harm reduction settings. Here we present a clinical series of xylazine-involved overdose and share the clinical approach and lessons learned by a community overdose response team in Tijuana, Mexico amidst the arrival of xylazine.
View Article and Find Full Text PDFExercise is recommended in the treatment of type 2 diabetes and can improve insulin sensitivity. However, previous evidence suggests that exercise at different times of the day in people with type 2 diabetes may have opposing outcomes on glycaemia. Metformin is the most commonly prescribed initial pharmacological intervention in type 2 diabetes, and may alter adaptions to exercise.
View Article and Find Full Text PDFSpindle Cell-Predominant Trichodiscoma With Palisading Arrangement: A Rare Variant.
Am J Dermatopathol
November 2023
Article Synopsis
- Spindle cell-predominant trichodiscoma (SCPT) is a benign skin tumor that typically appears as dome-shaped papules on the face, especially around the nose.
- The variant discussed in the article features a unique palisaded arrangement of spindle cells within a supportive fibromyxoid stroma, setting it apart from other forms of SCPT.
- The study highlights a rare case in a middle-aged man, whose biopsy revealed distinct features that help differentiate this variant from schwannomas, including specific immunohistochemical staining patterns.
Kaposi sarcoma (KS) is an endothelial tumor associated with human herpesvirus 8. Cutaneous lesions can present with pink or purple patches, plaques, and nodules which can be ulcerated. The main subtypes of KS generally have similar histologic appearances, with spindle cells and expression of human herpesvirus 8 being characteristic features.
View Article and Find Full Text PDFBackground: The use of pulse dose corticosteroid therapy (PDCT) in children for treatment of alopecia areata (AA) has been reported, but dosing regimens are not well-established. We aim to evaluate the available literature regarding the utilization and various dosing regimens of PDCT, as well as associated side effects, in the treatment of AA in children.
Methods: We performed a systematic review of studies describing the use of PDCT for the treatment of AA in children.