Objective: This study aimed to evaluate the association between asthma prevalence and outdoor air pollution in children in Latin America and the Caribbean.
Data Sources: We searched studies in global and regional databases: PubMed, Scopus, LILACS and SciELO.
Study Selection: Articles following a cross-sectional design, studying children from 0 to 18 years old, and comparing the prevalence of asthma in two or more areas of LAC countries with different air pollution levels were included.
Background: Several observational studies have suggested that outdoor air pollution may induce or aggravate asthma. However, epidemiological results are inconclusive due to the presence of numerous moderators which influence this association. The goal of this study was to assess the relationship between outdoor air pollutants and moderate or severe asthma exacerbations in children and adults through a systematic review and multilevel meta-analysis.
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