Oral Tolerance Induced by Heat Shock Protein 65-Producing Mitigates Inflammation in Infection.

Cutaneous leishmaniasis caused by induces a pronounced Th1 inflammatory response characterized by IFN-γ production. Even in the absence of parasites, lesions result from a severe inflammatory response in which inflammatory cytokines play an important role. Different approaches have been used to evaluate the therapeutic potential of orally administrated heat shock proteins (Hsp).