Publications by authors named "Breden A"

Article Synopsis
  • A study analyzed the impact of the COVID-19 pandemic on the length of hospital stays (LOS) for healthy, term infants after birth and their rehospitalization rates within a week of discharge.
  • Results showed that short hospital stays increased significantly during the pandemic, from 28.5% to 43%, but the rehospitalization rate slightly decreased (1.2% to 1.1%), indicating that shorter stays might be safe for healthy infants.
  • The findings suggest that although families opted for shorter hospital stays during COVID-19, this change did not lead to a rise in rehospitalization, highlighting a need for further research on other potential outcomes.
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The purpose of this study was to determine the best estimate of glomerular filtration rate (GFR) to adjust vancomycin (VAN) dosage in critically ill patients. Seventy-eight adult intensive care unit patients received a 15 mg/kg loading dose of VAN plus a 30 mg/kg/day continuous infusion. Steady-state concentration was measured 48 hours later and the dose was adjusted to obtain a target concentration ranging from 20 to 25 mg/l.

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Article Synopsis
  • The study reviewed necrotizing enterocolitis (NEC) cases in full-term neonates on Reunion Island from 2000 to 2012, finding that 12.4% of NEC cases were in full-term infants born at a mean gestational age of 36.8 weeks.
  • The majority of cases had identifiable underlying causes, with surgery needed in 37.5% of patients and a high overall survival rate of 88.8%.
  • The onset of NEC in full-term infants was later than what literature suggests but still earlier than in premature infants, indicating the need for further research to understand this condition better and reduce mortality.
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Introduction: The aim of this study, performed in an intensive care unit (ICU) population with a normal serum creatinine, was to estimate urinary creatinine clearance (CLCR) in a population of polytrauma patients (PT) through a comparison with a population of non trauma patients (NPT).

Methods: This was a retrospective, observational study in a medical and surgical ICU in a university hospital. A total of 284 patients were consecutively included.

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Altered pharmacokinetics in burn patients may affect antibiotic plasma concentrations. Typical once-daily dosing (ODD) of 15 mg/kg amikacin (AMK) in burn patients does not always produce peak concentrations (C(max)) reaching the therapeutic objective of six to eight times the minimal inhibitory concentration (MIC). We recorded plasma concentrations following administration of 20 mg/kg AMK in burn patients and studied factors affecting pharmacokinetics.

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The occupational therapist is vital to providing a complete assessment and thorough treatment of the population with eating disorders. Symptoms and etiology that effect the occupational therapist's reasoning are explored followed by the theoretical frameworks used and specific group intervention at the Sheppard and Enoch Pratt Hospital. Two case studies conclude the article.

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