D-hormone and its significance for function of prostate gland (literature review and personal observations).

Objective: Aim: The aim of this article is to present literature data and personal research of the role of D-hormoneon the functioning of the male reproductive system, and more specifically of the prostate gland, as well as the use of this vitamin D during the complex and independent treatment of benign prostatic hyperplasia in preclinical studies and clinical practice.

Patients And Methods: Materials and Methods: The collection of relevant data were done using the scientific databases Pubmed, Google Scholar. A manual search on reproductive endocrinology and pharmacology sources were also conducted for related published studies .

THE STATE OF PROOXIDANT-ANTIOXIDANT BALANCE IN PROSTATE GLAND OF RATS WITH CRYOTRAUMA AND ITS CORRECTION WITH DRUGS OF NATURAL ORIGIN.

The article deals with evaluation of the prooxidant-antioxidant balance in the prostate gland of rats with prostate cryotrauma caused with the help of Wartner® on the basis of biochemical studies results. The restored glutathione, lipid hydroperoxides, diene conjugates, TBA products were investigated in the prostate homogenate, together with the state of sperm according to the following characteristics: quantity, pathological forms, motility and time of its preservation. Correction was performed using the following drugs: Chondroitin sulfate, Tribestan, Chondroitin sulfate in combination with Tribestan, Prostoplant forte and Bioglobin-U.

[INVESTIGATIONS OF SUBMICROSCOPIC ARCHITECTONICS SERTOLI AND LEYDIG CELLS AFTER HYDROCHLORIDE SEROTONIN DESTRUCTIVE IMPACT AND THE POSSIBILITY OF CORRECTION BY STIMULANTS OF METABOLIC PROCESSES].

The results of study of ultrastructural changes in the Sertoli cells and Leydig's cells organelles after destructive influence of the serotonin hydrochloride and under influence bioglobin-U have been presented. It was shown that serotonin hydrochloride causes mitochondrial dysfunction and activates intracellular catabolic processes on the intracellular level. Bioglobin-U increases the activity and reparative synthetic reactions, reduced the degree of mitochondrial dysfunction and catabolic processes and activate the Leydig cell metabolism, and significantly reduces the number of foci destruction membranes of the endoplasmic reticulum, mitochondrial, and membranes of nucleus on the background of serotonin hydrochloride.

[The impact of male phytoestrogenization on the somato-sexual development and fertility of the offsprings in rats].

The effect of phytoestrogen-rich diet administered to male rats in a dose 20 mg/kg of body weight for 30 days with the mixture of phytoestrogens on reproductive function of male offspring and the effect of additional phytoestrogenization during milk feeding have been investigated. It was shown that male phytoestrogenization leads to feminization of the offsprings. Specifically, at birth, the ano-genital distance in males was less than that measured in control rats: (2.