Publications by authors named "Breanne M Mefford"
Article Synopsis
- Volume overload (VO) is a common issue in ICUs, often leading to negative health outcomes, prompting this study to explore a pharmacist-led initiative to optimize medication diluent volumes.
- The pilot study was conducted in two phases, comparing fluid balance and medication administration between a pre-implementation group and a post-implementation group in a medical ICU.
- Although the post-implementation group showed a reduction in antimicrobial diluent volumes, overall fluid balance did not significantly differ between the groups, indicating that optimizing diluent volumes alone may not effectively manage VO, and suggesting the need for broader strategies in future research.
Cefepime induced neurotoxicity (CIN) is commonly associated with renal dysfunction, however CIN can occur in patients with normal renal function or renally dose-adjusted regimens. Few reports of this kind have obtained cefepime concentrations to assist in diagnosis. A 42-year old female with a complex past medical history was transferred to our facility with chief complaint of worsening shock and respiratory failure, and the patient was also noted to be hypernatremic, experiencing diabetic ketoacidosis (DKA), and acute kidney injury (AKI).
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