Publications by authors named "Brayan S Aristizabal-Carmona"

Introduction: Both the induction and inhibition of cytochrome P450 are associated with multiple pharmacological interactions, which can lead to loss of efficacy or increase the risk of adverse drug reactions.

Objective: The aim was to determine the prescription patterns of cytochrome P450-inducing and -inhibiting drugs and their contraindicated and major pharmacological interactions in a group of patients from Colombia.

Methods: This cross-sectional observational study included patients who received drugs that induce or inhibit metabolism and examined their contraindicated and major pharmacological interactions.

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Skin and soft tissue infections are one of the main causes of consultations worldwide. The objective was to determine the treatment of a group of patients with uncomplicated skin and soft tissue infections in Colombia. Follow-up study of a cohort of patients with skin infections who were treated in the Colombian Health System.

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Article Synopsis
  • - The study analyzed prescription patterns for urinary incontinence (UI) treatments in a cohort of 9,855 patients from the Colombian Health System, predominantly elderly women aged 72 on average.
  • - The most common form of UI was unspecified (83.2%), and a significant portion (37.2%) received pharmacological treatment, mainly consisting of bladder antimuscarinics (22.6%) and mirabegron (15.6%).
  • - Findings revealed that risky prescriptions, particularly for bladder antimuscarinics among older patients and those with other health conditions, were frequent, highlighting the need for careful medication management.
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  • * Out of 74,603 patients, fluconazole was the most prescribed antifungal, often for conditions like vaginitis, while nearly 30% of prescriptions were for unapproved uses, particularly with ketoconazole.
  • * Factors such as being male, under 18, living in the Caribbean, and having chronic health conditions increased the likelihood of receiving antifungals for unapproved indications, whereas having serious illnesses like diabetes or HIV decreased it.
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Objective: Autoimmune idiopathic inflammatory myopathies (IIMs) are a group of pathologies that are generally characterized by muscle weakness. Their treatment involves glucocorticoids and immunosuppressants. The aim was to identify differences and similarities in the pharmacological management of a group of patients with autoimmune IIMs according to the type of disease, sex, age group, and city of residence in Colombia from 2020 to 2021.

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The impact of COVID-19 prompted a race to find a treatment that would reduce its mortality. Most studies have not shown favorable results for many of these drugs, but they are still used. The aim as to determine the differences and similarities in the hospital pharmacological management of patients with COVID-19 according to sex, age group, and geographical region of Colombia, 2020-2021.

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Background: Helicobacter pylori infection can cause gastritis, gastric ulcers, duodenal ulcers, and gastric cancer. Its treatment involves different medications, but resistance to these treatments is increasing. It is currently considered a public health problem.

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In recent years, and now especially with the arrival of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), there has been increased interest in understanding the role of bats in the dynamics of transmission and origin of this pandemic agent. To date, no systematic reviews have been published on this topic. This systematic review aimed to summarize and highlight the frequency of bat infections reported in currently available observational studies for coronavirus.

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