Use of a Novel Artificial Intelligence System Leads to the Detection of Significantly Higher Number of Adenomas During Screening and Surveillance Colonoscopy: Results From a Large, Prospective, US Multicenter, Randomized Clinical Trial.

Introduction: Adenoma per colonoscopy (APC) has recently been proposed as a quality measure for colonoscopy. We evaluated the impact of a novel artificial intelligence (AI) system, compared with standard high-definition colonoscopy, for APC measurement.

Methods: This was a US-based, multicenter, prospective randomized trial examining a novel AI detection system (EW10-EC02) that enables a real-time colorectal polyp detection enabled with the colonoscope (CAD-EYE).

A randomized, double-blind, placebo-controlled trial of aldafermin in patients with NASH and compensated cirrhosis.

Background And Aims: Aldafermin, an engineered analog of the human hormone FGF19, improves liver histology in patients with noncirrhotic NASH; however, its efficacy and safety in compensated cirrhosis is unknown. No drug has yet to demonstrate benefit in the compensated NASH population.

Approach And Results: In this multicenter, double-blind, placebo-controlled, phase 2b trial, 160 patients with compensated NASH cirrhosis were randomized to aldafermin 0.

Pharmacist and Homeless Outreach Engagement and Non-medical Independent prescribing Rx (PHOENIx): a study protocol for a pilot randomised controlled trial.

Introduction: The number of people experiencing homelessness (PEH) is increasing worldwide. Systematic reviews show high levels of multimorbidity and mortality. Integrated health and social care outreach interventions may improve outcomes.

Firefighter Well-Being Defined and Operationalized at the Organizational and Worker Level: A Qualitative Study.

Objective: The aim of the study is to define and explore organizational- and worker-level factors of firefighter well-being.

Methods: Qualitative data were collected using interviews and focus group sessions among 17 career firefighters across 4 fire departments. Interviews were recorded and transcribed, and a general inductive approach was used to code similar concepts into themes.

Walking Meeting Effects on Productivity and Mood Among White-Collar Workers: Evidence From the Walking Meeting Pilot Study.

Objective: Walking Meetings (WaM) have shown to be acceptable, feasible, and implementable among white-collar workers. This pilot study examines the effects of WaM on worker mood, productivity, and physical activity.

Methods: Eighteen white-collar workers were recruited from a university in Florida.

Musculoskeletal Pain and Interest in Meditation and Yoga in Home Health Aides: Evidence From the Home Health Occupations Musculoskeletal Examinations (HHOME) Study.

Home healthcare aides (HHAs) are a growing U.S. workforce highly susceptible to workplace stressors and musculoskeletal pain.

Association between positive and negative affect and musculoskeletal pain among US home health aides.

As the US population ages, there is an expected increase in demand for home health aides (HHAs); therefore, it is important to ensure their occupational well-being. Previous studies have demonstrated associations between negative emotions and musculoskeletal pain. Using survey data collected from 285 HHAs, we characterize the association between affect and musculoskeletal pain.

Opportunities for Increased Physical Activity in the Workplace: the Walking Meeting (WaM) Pilot Study, Miami, 2015.

Introduction: Despite the positive impact walking has on human health, few opportunities exist for workers with largely sedentary jobs to increase physical activity while at work. The objective of this pilot study was to examine the implementation, feasibility, and acceptability of using a Walking Meeting (WaM) protocol to increase the level of work-related physical activity among a group of sedentary white-collar workers.

Methods: White-collar workers at a large university were invited to participate in a newly developed WaM protocol.

Having friends and feeling lonely: a daily process examination of transient loneliness, socialization, and drinking behavior.

Loneliness is a well-known indicator of relationship deficits, with potentially severe consequences on health and well-being (Perlman & Peplau, 1981). Research has used cross-sectional methods to examine behavioral consequences of loneliness (e.g.

Daily mood-drinking slopes as predictors: a new take on drinking motives and related outcomes.

Motivational models of alcohol consumption have articulated the manner in which positive and negative experiences motivate drinking in unique social contexts (e.g., M.

Propofol infusion syndrome in a super morbidly obese patient (BMI = 75).

Propofol infusion syndrome (PRIS) is a rare but often fatal complication as a result of large doses of propofol infusion (4-5 mg/kg/hr) for a prolonged period (>48 h). It has been reported in both children and adults. Besides large doses of propofol infusion, the risk factors include young age, acute neurological injury, low carbohydrate and high fat intake, exogenous administration of corticosteroid and catecholamine, critical illness, and inborn errors of mitochondrial fatty acid oxidation.

Evidence for positive mood buffering among college student drinkers.

Positive experiences play an important role in buffering the effects of negative experiences. Although this process can play out in a myriad of contexts, the college context is one of particular importance because of significant concerns about student stress levels and alcohol abuse. Building on evidence that at least some students drink in response to negative experiences, we considered the possibility that positive moods would moderate college student negative mood-drinking relationships.

Validation of microbial recovery from disinfectants.

We evaluated the efficacy of different neutralizing solutions for use in disinfectant efficacy assays. Our approach used comparisons between the recoveries of low inocula in different treatment populations. The challenge organisms employed were those described by the AOAC for use in determining germicidal, tuberculocidal, sporicidal, and fungicidal activity of disinfectants.

Protozoal colonization of the intestinal tract in institutionalized Romanian children.

To determine the prevalence of intestinal parasitic infections in 92 Romanian children institutionalized at Colentina Hospital (Bucharest, Romania) and at the Dystrophic Center (Vidra, Romania), medical charts were reviewed and complete physical examinations were performed. The nutritional status of each child was evaluated, and their sera were tested for the presence of antibodies to human immunodeficiency virus (HIV) and Cryptosporidium. Fecal samples were collected in 10% formalin and examined by an immunofluorescent assay and by trichrome staining for intestinal parasites.

Type of closure prevents microbial contamination of cosmetics during consumer use.

The dispensing closure used for containers plays an important role in protecting cosmetics from in-use microbial contamination. This hypothesis was tested by aseptically packing unpreserved shampoo and skin lotion into containers with three different closure types which provided various degrees of protection against consumer and environmental microbial insults. Shampoo was packed in containers with slit-cap (n = 25), flip-cap (n = 25), or screw-cap (n = 28) closures.

Idiopathic thrombocytopenic purpura in the older adult patient.

Forty adults with idiopathic thrombocytopenic purpura (ITP), aged over 45 years, were seen from March 1954 to December 1983 at the Medical College of Georgia. All patients had bleeding manifestations at presentation. Twenty-one of 40 (52.

Idiopathic thrombocytopenic purpura in adults.

Idiopathic thrombocytopenic purpura (ITP) is a primary immune thrombocytopenia that is typically manifested in adults by acute bleeding, severe thrombocytopenia, and normal to increased megakaryocytes in the bone marrow. Labeling studies suggest that most patients with ITP have an IgG antibody directed against the platelet membrane resulting in sequestration in the spleen, and that sequestration in other organs such as the liver bodes a poor prognosis. Splenectomy and/or corticosteroids remain the mainstay of therapy, with permanent remissions induced in 75% of patients.

Correlation of in vitro challenge testing with consumer use testing for cosmetic products.

An in vitro microbial challenge test has been developed to predict the likelihood of consumer contamination of cosmetic products. The challenge test involved inoculating product at four concentrations (30, 50, 70, and 100%) with microorganisms known to contaminate cosmetics. Elimination of these microorganisms at each concentration was followed over a 28-day period.

Cefoxitin therapy for Mycobacterium fortuitum bacteremia with associated granulomatous hepatitis.

Mycobacterium fortuitum bacteremia with granulomatous hepatitis complicating home cyclic parenteral nutrition through an indwelling Broviac catheter occurred in a 41-year-old woman. She was successfully treated with intravenous cefoxitin and removal of the indwelling central catheter. The granulomatous hepatitis occurred in the apparent absence of mycobacteria from the liver.

Growth Kinetics and Yield Coefficients of the Extreme Thermophile Thermothrix thiopara in Continuous Culture.

Thermothrix thiopara did not appear to be stressed at high temperature (72 degrees C). Both the actual and theoretical yields were higher than those of analogous mesophilic sulfur bacteria, and the specific growth rate (mu(max)) was more rapid than that of most autotrophs. The specific growth rate (0.

Evaluation of a proposed surface colonization equation usingThermothrix thiopara as a model organism.

The colonization equation shown below was evaluated usingThermothrix thiopara as a model organism.[Formula: see text] where: N=number of cells on surface (cells field(-1)); A = attachment rate (cells field(-1) h(-1)); M=specific growth rate (h(-1)); t=incubation period (h).Previous studies of microbial surface colonization consider attachment and growth independently.

Quantitation of microbial growth on surfaces.

An equation describing the initial phases of microbial surface colonization is presented. Simultaneous microbial attachment and growth are considered as the primary components of colonization. A table is given that permits determination of growth rate from the density and distribution of cells present on surfaces after incubation in situ.