GenoFig: a user-friendly application for the visualization and comparison of genomic regions.

Motivation: Understanding the molecular evolutionary history of organisms usually requires visual comparison of genomic regions from related species or strains. Although several applications already exist to achieve this task, they are either too old, too limited, or too complex for most user's needs.

Results: GenoFig is a graphical application for the visualization of prokaryotic genomic regions, intended to be as easy to use as possible and flexible enough to adapt to a variety of needs.

Does parental autonomy support mediate the relation between parent and infant executive function? A study of mothers and fathers in the Netherlands and China.

Parenting skills, such as Autonomy Support (AS), have been proposed as a potential mechanism explaining the intergenerational contiguity of Executive Function (EF). However, few studies have focused on mothers and fathers among non-Western families. The current study investigated the role of maternal and paternal AS in the relation between parental EF and infant EF at 14 months of age among 123 Dutch and 63 Chinese first-time mothers and fathers and their infants.

Narrative coherence across the transition to parenthood: Primiparous parents' representations of their child in relation to parental sensitivity.

Narrative coherence reflects parents' ability to provide a believable, clear, relevant, and internally consistent story about their child. Parents demonstrating more narrative coherence have been theorized to show higher parental sensitivity, but this has not been examined in a normative sample, nor across the transition to parenthood, and only once in fathers. The aim of this study was to examine stability and change in narrative coherence across the transition to parenthood in mothers and fathers, as well as the relation between pre- and postnatal narrative coherence and postnatal parental sensitivity.

The role of infant attention and parental sensitivity in infant cognitive development in the Netherlands and China.

Infant attention and parental sensitivity are important predictors of later child executive function (EF). However, most studies have investigated infant and parent factors in relation to child EF separately and included only mothers from Western samples. The current study examined whether both infant attention at 4 months and parental sensitivity at 4 and 14 months were related to infant EF (i.

Lipopolysaccharide core type diversity in the species in association with phylogeny, virulence gene repertoire and distribution of type VI secretion systems.

is a very versatile species for which diversity has been explored from various perspectives highlighting, for example, phylogenetic groupings and pathovars, as well as a wide range of O serotypes. The highly variable O-antigen, the most external part of the lipopolysaccharide (LPS) component of the outer membrane of , is linked to the innermost lipid A through the core region of LPS of which five different structures, denominated K-12, R1, R2, R3 and R4, have been characterized so far. The aim of the present study was to analyse the prevalence of these LPS core types in the species and explore their distribution in the different phylogenetic groups and in relationship with the virulence gene repertoire.

Draft Genome Sequences of 142 Mycobacterium avium subsp. Strains Isolated from Naturally Infected Dairy Cattle.

Mycobacterium avium subsp. is the etiological agent of Johne's disease in ruminants. Here, we report the annotated draft genome sequences of 142 M.

Whole-Genome Analysis of subsp. IS -.

subsp. () is the etiological agent of Johne's disease in ruminants. The IS insertion sequence (IS) has been used widely as an epidemiological marker and target for PCR diagnosis.

Engineering Synthetic Lipopeptide Antigen for Specific Detection of subsp. Infection.

Unlike other MAC members, subsp. (MAP) does not produce glycopeptidolipids (GPL) on the surface of the cell wall but a lipopentapeptide called L5P (also termed Lipopeptide-I or Para-LP-01) characterized in C-type (bovine) strains. This lipopeptide antigen contains a pentapeptide core, D-Phenylalanine-N-methyl-L-Valine-L-Isoleucine-L-Phenylalanine-L-Alanine, in which the N-terminal D-Phenylalanine is amido-linked with a fatty acid (C18-C20).

Attitudes about child maltreatment in China and the Netherlands.

Background: Definitions of child maltreatment vary between studies, and few are informed by research in non-Western countries.

Objective: We examined attitudes about child maltreatment in China and the Netherlands.

Participants And Setting: The sample consisted of 304 participants from three groups (mothers, fathers, and teachers) and two countries (China and the Netherlands).

Genetic Diversity Among Subspecies Revealed by Analysis of Complete Genome Sequences.

comprises four subspecies that contain both human and veterinary pathogens. At the inception of this study, twenty-eight genomes had been annotated as RefSeq genomes, facilitating direct comparisons. These genomes represent strains from around the world and provided a unique opportunity to examine genome dynamics in this species.

Feature of Adhesins Produced by Human Clinical Isolates of , subsp. and Closely Related Species.

The complex includes two closely related species, and . They are opportunistic pathogens in humans and responsible for severe disease in a wide variety of animals. Yet, little is known about factors involved in their pathogenicity.

The effect of the still-face paradigm on infant behavior: A cross-cultural comparison between mothers and fathers.

Most still-face paradigm (SFP) studies have been done in Western families with infant-mother dyads. The present study investigated the SFP pattern in 123 Dutch and 63 Chinese 4-month-old infants with mothers and fathers. The classic SFP effect was found for positive affect and gaze in both countries.

Dataset on maternal attitudes about child maltreatment in nine countries using a Q-sort methodology.

Analyses of the present data are reported in the article "Crossing Boundaries: A Pilot Study of Maternal Attitudes about Child Maltreatment in Nine Countries" [8]. Data were collected during home visits using the Maltreatment Q-Sort (MQS). A total of 466 mothers from nine different countries gave their opinion about child maltreatment by sorting 90 cards with parenting behaviors taken from the literature that reflect four types of child maltreatment, into 9 evenly distributed stacks (with 10 cards each) from least to most harmful for the child.

The complete genome sequence of Mycobacterium bovis Mb3601, a SB0120 spoligotype strain representative of a new clonal group.

Mycobacterium bovis strain Mb3601 was isolated from the lymph node of an infected bovine in a bovine tuberculosis highly enzoonotic area of Burgundy, France. It was selected to obtain a complete genome for a new clonal complex, mainly constituted by SB0120-spoligotype strains that we propose to name "European 3". It was recently described as "clonal group I" based on whole-genome SNP analysis of 87 French strains.

Whole-Genome Sequencing Confirms the Coexistence of Different Colonizing Group B Isolates Underscored by CRISPR Typing.

is a major pathogen and is the leading cause of neonatal infections in industrialized countries. The diversity of strains isolated from two pregnant women was investigated. Here, we present the draft genome sequences of strains W8A2, W8A6, W10E2, and W10F3, obtained in order to ascertain their phylogenetic affiliation.

Transmission Network of Deer-Borne Infection Revealed by a WGS Approach.

Bovine tuberculosis (TB) is a zoonotic disease, mainly caused by . France was declared officially TB free in 2001, however, the disease persists in livestock and wildlife. Among wild animals, deer are particularly susceptible to bovine TB.

Crossing boundaries: A pilot study of maternal attitudes about child maltreatment in nine countries.

Background: Definitions of child maltreatment vary widely between studies, and even more so between different cultural contexts.

Objective: In this pilot study, we examine between-country variations in maternal notions about what constitutes child maltreatment.

Participants And Setting: The sample consisted of 466 mothers recruited in Chile, China, Greece, Iran, the Netherlands, Portugal, South Africa, Turkey, and Uruguay.

MAC-INMV-SSR: a web application dedicated to genotyping members of Mycobacterium avium complex (MAC) including Mycobacterium avium subsp. paratuberculosis strains.

Genotyping of Mycobacterium avium subsp. paratuberculosis (Map) is an indispensable tool for surveillance of this significant veterinary pathogen. For Map, multi-locus variable number tandem repeat analysis (MLVA) targeting mycobacterial interspersed repetitive units (MIRUs) and other variable number variable-number tandem repeats (VNTRs) was established using 8 markers.

Thinking about you baby: Expectant parents' narratives suggest prenatal spillover for fathers.

The coherence of parents' narratives about their children, which is the extent to which descriptions are accepting, consistent and complex, are thought to reflect optimal information processing of interpersonal relations and as such facilitate sensitive and responsive parenting. However, despite recent meta-analytic findings that have demonstrated links between the nature of prenatal thoughts and feelings about the unborn infant and later parenting, studies have yet to examine the narrative coherence of expectant parents' descriptions of their infant and future parent-child relationship. This study reports on the novel use of the 5-minute speech sample to capture variation in the coherence of 400 first-time expectant parents' narratives describing their unborn infant and future relationship with them.

Context matters: Maternal and paternal sensitivity to infants in four settings.

To date, results have been inconsistent in whether mothers show higher parental sensitivity to their infant than fathers do. The context in which sensitivity is measured may play a role in these inconsistent findings, but this has not been examined yet. The aim of the current study was to test context as a source of variability in parental sensitivity, comparing maternal and paternal sensitivity to infants in four different observational settings.

Accurate Phylogenetic Relationships Among Strains Circulating in France Based on Whole Genome Sequencing and Single Nucleotide Polymorphism Analysis.

In recent years the diversity of the French population responsible for bovine tuberculosis (bTB) outbreaks since 1970 has been described in detail. To further understand bTB evolution in France, we used single nucleotide polymorphisms (SNPs) based on whole genome sequence versus classical genotyping methods in order to identify accurate phylogenetic relationships between strains. Whole genome sequencing was carried out on a selection of 87 strains which reflect the French population's genetic diversity.

Venous thromboembolic events during warm autoimmune hemolytic anemia.

Thrombotic manifestations are a hallmark of many auto-immune diseases (AID), specially of warm autoimmune hemolytic anemia (wAIHA), as 15 to 33% of adults with wAIHA experience venous thromboembolic events (VTE). However, beyond the presence of positive antiphospholipid antibodies and splenectomy, risk factors for developing a VTE during wAIHA have not been clearly identified. The aim of this retrospective study was to characterize VTEs during wAIHA and to identify risk factors for VTE.

Environmental subsp. Hosted by Free-Living Amoebae.

subsp. is responsible for paratuberculosis in animals. This disease, leading to an inflammation of the gastrointestinal tract, has a high impact on animal health and an important economic burden.

Draft Genome Sequences of Three Strains Identified in Cattle and Wildlife in France.

is the etiologic agent of bovine tuberculosis, a chronic infectious disease affecting livestock, wild animals, and sometimes humans. We report here three draft genome sequences of strains of spoligotypes SB0821 and SB0134, isolated from wildlife but circulating in wildlife-livestock multihost systems, and SB0121, circulating exclusively in cattle.