Publications by authors named "Brandy M Calhoun"
Article Synopsis
- * The study focused on the high-resolution structures of seven IVA hemagglutinin (HA) proteins, crucial for the virus's ability to infect host cells, and highlighted conserved receptor binding sites that help the virus evade antibody detection.
- * The findings revealed that changes in HA proteins can affect antibody binding, providing valuable insights for the development of future anti-influenza vaccines.
Acetyl CoA synthetases (ACSs) are cyl-CoA/RPS/uciferase (ANL) superfamily enzymes that couple acetate with CoA to generate acetyl CoA, a key component of central carbon metabolism in eukaryotes and prokaryotes. Normal mammalian cells are not dependent on ACSs, while tumor cells, fungi, and parasites rely on acetate as a precursor for acetyl CoA. Consequently, ACSs have emerged as a potential drug target.
View Article and Find Full Text PDF