Publications by authors named "Brandon Paarwater"
Inhaled particulate matter affects immune responsiveness of human lung phagocytes to mycobacteria.
Am J Physiol Lung Cell Mol Physiol
September 2021
Article Synopsis
- Smoke and air pollution can harm our lungs and weaken our immune system, making it harder to fight infections.
- Scientists studied special lung cells that were loaded with pollution particles and tested how well they could respond to mycobacterial infections.
- They found that while these polluted cells could still eat bacteria, they produced less important immune signals that help fight off infections, which could affect their ability to protect us in the long run.
Primary immunodeficiency disorders (PIDs) are inborn errors of immunity (IEI) that cause immune system impairment. To date, more than 400 single-gene IEI have been well defined. The advent of next generation sequencing (NGS) technologies has improved clinical diagnosis and allowed for discovery of novel genes and variants associated with IEI.
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