Hydroxychloroquine retinopathy after short-term therapy.

Purpose: To report an unusual case of hydroxychloroquine toxicity after short-term therapy.

Methods: Observational case report.

Results: A 56-year-old woman presented to the Ophthalmology Clinic at Walter Reed Army Medical Center (WRAMC) with a 6-month history of gradually decreasing vision in both eyes.

Periorbital nodular fasciitis arising during pregnancy.

Nodular fasciitis (NF) is a benign proliferation of fibroblasts and myofibroblasts that rarely occurs in the periorbital region. We report what we believe to be the first case of periorbital NF associated with pregnancy. A case of intravascular fasciitis, a NF variant, has been reported during pregnancy, but it was not located in the periorbital region.

Closed globe macular injuries after blasts in combat.

Purpose: To describe the macular findings after closed globe ocular injuries sustained from blasts.

Methods: A retrospective chart review from February 2003 to March 2010 of all soldiers with closed globe ocular injuries sustained during combat with macular findings of trauma on examination was completed.

Results: There were 36 eyes that met the inclusion criteria.

A retrospective review of oral low-dose sirolimus (rapamycin) for the treatment of active uveitis.

Purpose: The purpose of this study is to elicit the role of oral low-dose sirolimus as a corticosteriod-sparing agent for active uveitis.

Methods: A retrospective, interventional case series was performed by reviewing the clinical records of all patients treated with oral, low-dose sirolimus (1-4 mg daily) for severe uveitis. Data reviewed included symptomatic improvement, Snellen best-corrected visual acuity, corticosteroid requirement, sirolimus levels, intraocular inflammation, spectral-domain optical coherence tomography, and fluorescein angiogram.