Examining the Association between Immunosuppressants and Wound Healing: A Narrative Review.

Objective: To review how different classes of immunosuppressants affect wound healing.

Data Sources: A literature search was conducted in PubMed, Google Scholar, and the University of Calgary Health Sciences Library.

Study Selection: The researchers initially screened article titles using key words such as "immunosuppressive medication," "wound healing," and "immunosuppression.

An up-to-date evaluation of dolutegravir/abacavir/lamivudine for the treatment of HIV.

Introduction: There are more than 30 agents available for the treatment of HIV with guidelines shifting toward integrase strand transfer inhibitors (INSTIs) as part of first line therapy. The fixed dose combination of dolutegravir (DTG), abacavir (ABC), and lamivudine (3TC) is a convenient, well tolerated, and highly effective option for treating HIV infection and remains a first line therapy across several prominent guidelines.

Areas Covered: In this drug evaluation, the authors provide a comprehensive overview of DTG/ABC/3TC for the treatment of HIV including the pharmacokinetics, pharmacodynamics, efficacy, safety, and tolerability.