Publications by authors named "Brandon Gibb"

Research has shown that exposure to higher rates of neighborhood disadvantage and contextual threat increases risk for the development of psychopathology in youth, with some evidence that these effects may differ across racial/ethnic groups. Although studies have shown that direct exposure to stress impacts neural responses to threat-relevant stimuli, less is known about how neighborhood characteristics more generally (e.g.

View Article and Find Full Text PDF

Objective: Current models of depression risk in children include both family history and cognitive models of risk; however, these models are rarely integrated. This study aimed to address this gap by examining how cognitive vulnerabilities featured in the hopelessness theory of depression - negative inferential styles for the causes, consequences, and self-characteristic implications of negative events - may increase risk for the intergenerational transmission of depression. Specifically, we examined whether children of mothers with a history of major depressive disorder (MDD), compared to children of never-depressed mothers, exhibit more negative inferential styles and whether maternal history of MDD moderates prospective relations between children's inferential styles and depressive symptoms.

View Article and Find Full Text PDF

This study tested children's emotion recognition as a mediator of associations between their exposure to hostile and cooperative interparental conflict and their internalizing and externalizing symptoms. From 2018 to 2022, 238 mothers, their partners, and preschool children (M = 4.38, 52% female; 68% White; 18% Black; 14% Multiracial or another race; and 16% Latinx) participated in three annual measurement occasions.

View Article and Find Full Text PDF
Article Synopsis
  • Twin studies suggest that genetic factors account for 30-40% of the risk for depression, highlighting the role of heredity in this mental health condition.
  • Researchers evaluated polygenic scores (PGS) derived from UK Biobank data on a group of 210 adults of European ancestry to see how well these scores predict clinical depression-related traits.
  • Although some small associations were observed between the PGS and various depression traits, only the link to suicidal ideation remained significant after adjusting for multiple comparisons, suggesting that the current PGS is only modestly predictive of depression-related outcomes.
View Article and Find Full Text PDF

Reward processing deficits play a clear role in depression and depression risk. For example, more than a decade of research has shown that individual differences in initial reward responsiveness, indexed by the reward positivity (RewP) event-related potential (ERP) component, are associated with current depression and future depression risk. Mackin and colleagues' study builds on this previous literature by asking 2 key questions: (1) Is the magnitude of the impact of RewP on prospective changes in depressive symptoms similar during late childhood and adolescence? and (2) Are prospective links between RewP and depressive symptoms transactional, with depressive symptoms also predicting future change in RewP during this developmental window? These questions are important, because this is a time period during which rates of depression increase dramatically and when there are normative changes in reward processing.

View Article and Find Full Text PDF

Offspring of mothers with a history of major depressive disorder (MDD) are at high risk of developing the disorder themselves, yet specific mechanisms of risk remain unclear. One hypothesized mechanism is interpersonal stress, which has been shown to be elevated in offspring of mothers with a history of MDD. The goal of this study was to examine the role of a specific form of interpersonal stress, peer victimization (overt and relational).

View Article and Find Full Text PDF

Background: Theorists have proposed that the way children process social-emotional information may serve as a mechanism of risk for the intergenerational transmission of depression. There is growing evidence that infants and children of mothers with a history of major depressive disorder (MDD) during the child's life exhibit attentional avoidance of sad faces, which has been proposed as an early emerging emotion regulation strategy. In contrast, there is clear evidence that at-risk and depressed adolescents and adults exhibit difficulty disengaging attention from sad faces.

View Article and Find Full Text PDF

In this study, we sought to combine two lines of research to better understand risk for the intergenerational transmission of depression. The first focuses on the role of maternal criticism as a potential mechanism of risk for depression in youth while the second builds from interpersonal and stress generation models regarding the potential impact of youth depression on future escalations in maternal criticism. Specifically, we examined the role of maternal criticism within a transactional mediation model using data from a multi-wave study.

View Article and Find Full Text PDF

Familial risk for depression is associated with youth exposure to self-generated dependent stressful life events and independent events that are out of youth's control. Familial risk includes both genetic and environmental influences, raising the question of whether genetic influences, specifically, are associated with youth exposure to both dependent and independent stressful life events. To address this question, this study examined the relation between a genome-wide association study (GWAS)-derived depression-based polygenic risk score (DEP-PRS) and youth experiences of dependent and independent stress.

View Article and Find Full Text PDF

The goal of this study was to examine age-related differences in children's reward processing. Focusing on reward outcome processing, we used event-related potentials to examine substages of neural response to gain versus loss feedback in a sample of 7-11-year-old children (M = 9.67, SD = 1.

View Article and Find Full Text PDF

Parental criticism is linked to a number of detrimental child outcomes. One mechanism by which parental criticism may increase risk for negative outcomes in children is through children's neural responses to valenced information in the environment. The goal of the current study, therefore, was to examine the relation between maternal criticism and children's neural responses to monetary gains and losses.

View Article and Find Full Text PDF
Article Synopsis
  • Research indicates a connection between immune processes and psychological issues, particularly major depressive disorder (MDD), with a focus on specific symptoms like anhedonia rather than broad diagnostic categories.
  • * A study examining immune responses to endotoxins in participants found that higher levels of current anhedonia were linked to increased inflammation, while a history of recurrent MDD did not show this association.
  • * The results suggest that anhedonia may be a distinct symptom related to inflammation, making endotoxin-stimulated cytokine production a potential biological marker for current anhedonia.
View Article and Find Full Text PDF

Major depressive disorder (MDD) is a highly prevalent psychiatric disorder, and recurrent depression is associated with severe and chronic impairment. Identifying markers of risk is imperative to improve our ability to predict which individuals are likely to experience a recurrence. According to cognitive theories, biases in attention for affectively-salient information may serve as one mechanism of risk.

View Article and Find Full Text PDF

Biased attention to sad faces is associated with depression in adults and is hypothesized to increase depression risk specifically in the presence, but not absence, of stress by modulating stress reactivity. However, few studies have tested this hypothesis, and no studies have examined the relation between attentional biases and stress reactivity during adolescence, despite evidence that this developmental window is marked by changes in depression risk, stress, and the function of attention. Seeking to address these limitations, the current study examined the impact of adolescents' sustained attention to facial displays of emotion on individual differences in both mood reactivity to real-world stress and physiological (i.

View Article and Find Full Text PDF

Introduction: Although social anxiety symptoms and exposure to maternal major depressive disorder (MDD) have each been conceptualized as key contributors to the development of depression symptoms in youth, these risk factors have not been integrated into a single model of risk. The current study evaluated a two-hit model of risk to determine whether the impact of social anxiety on prospective changes in youth depressive symptoms is stronger among youth exposed to maternal MDD than among those of never-depressed mothers.

Methods: Participants were youth (aged 8-14 at baseline, 50.

View Article and Find Full Text PDF

The Reward Positivity (∆RewP) event-related potential (ERP), generally quantified as the difference between neural responsiveness to monetary gains (RewP-Gain) and losses (RewP-Loss) is commonly used as an index of neural reward responsiveness. Despite the popularity of this ERP component in studies of reward processing, knowledge about the role of state-related influences on the ∆RewP is limited. The present study examined whether ∆RewP amplitudes may differ based on when during the day they are assessed and whether age or sex would moderate this link.

View Article and Find Full Text PDF