Publications by authors named "Brandon Eden"
Inferior vena cava filling defects are common findings on computed tomography and magnetic resonance imaging, and accurate determination of pseudo, benign, or malignant thrombus is essential for clinical management. Inferior vena cava thrombosis involvement extending into the right atrium is a rare presentation of renal cell carcinoma. The degree of inferior vena cava and right atrium involvement is critical in determining management and prognosis of patients.
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- Study aimed to assess if using enteral acetaminophen instead of parenteral affects pain management, narcotic use, or PACU discharge times in non-cardiac surgery patients.
- The research was a retrospective cohort study analyzing data from around 24,701 patients before and after implementing the initiative at a tertiary academic medical center.
- Results showed an increase in enteral acetaminophen use and a decrease in parenteral use, but no significant changes in narcotic consumption or PACU discharge times were found, despite a lower median acetaminophen dose noted post-initiative.
More effective delivery of non-steroidal anti-inflammatory drugs (NSAIDs) to the brain could treat the underlying inflammatory pathology of a range of CNS diseases and conditions. Use of a blood-brain barrier shuttle such as the N-benzylamide moiety, which has been largely unexplored for this purpose, could improve the brain bioavailabilities of NSAIDs. A series of novel N-benzylamide NSAID conjugates was synthesized via a three-step process with a microwave-assisted bimolecular nucleophilic substitution as the final step.
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