Total Synthesis of (+)-Discorhabdin V.

The discorhabdin natural products are a large subset of pyrroloiminoquinone alkaloids with a myriad of biological activities. Despite garnering much synthetic attention, few members have thus far been completed, particularly those featuring a bridging carbon-nitrogen bond that is found in numerous discorhabdins, including discorhabdin V. Herein we report the first total synthesis and full stereochemical assignment of (+)-discorhabdin V.

Going Homoleptic: Synthesis and Full Characterization of Stable Manganese Tetranitrosyl Cation Salts.

Although similar to carbon monoxide, the chemistry of homoleptic nitrogen monoxide complexes is fundamentally unexplored compared to their carbonyl analogues. Herein we report the synthesis of the first truly homoleptic transition-metal nitrosyl cation as the salt of the weakly coordinating anions (WCAs) [Al(OR ) ] and [F{Al(OR ) } ] (R =C(CF ) ). These salts are easily accessible in good yields, phase pure, and were fully characterized by IR/Raman, NMR and UV/Vis spectroscopy as well as single-crystal and powder X-ray diffraction.

Structural and electrochemical comparison of trinuclear ruthenium oxo clusters [Ru(OAc)O(L)]and [Ru(OAc)O(L)(CO)] (L = imidazole, benzimidazole, and 4-phenylpyridine).

The triruthenium oxo clusters [Ru(OAc)O(L)] and [Ru(OAc)O(L)(CO)] possess unique electronic characteristics that vary based on the ligands L. Here we report an investigation of the structural, electrochemical, and optical properties of clusters with imidazole, benzimidazole, and 4-phenylpyridine ligands. The complexes [Ru(OAc)O(L)] [1: L = imidazole (im); 2: L = benzimidazole (benzim); 3: L = 4-phenylpyridine (4PP)] and [Ru(OAc)O(L)(CO)] (1-CO and 3-CO) were synthesized by reaction of either [Ru(OAc)O(MeOH)] or [Ru(OAc)O(MeOH)(CO)], respectively, with the corresponding heterocycle.