Publications by authors named "Brandon C James"
Article Synopsis
- Chronic alcohol use disorder (AUD) leads to neurodegeneration in the brain, primarily through mechanisms like chronic neuroinflammation affecting neuron survival.
- Research has identified the gene α-synuclein as a potential player in AUD, but its specific role in alcohol-related brain damage remains unclear.
- A systematic review found a significant gap in studies connecting α-synuclein and neuroinflammation specifically to AUD, with most research instead focusing on the TLR4 signaling pathway and other inflammatory responses in different neurodegenerative diseases.*