How adherence to public health measures shapes epidemic spreading: A temporal network model.

The COVID-19 pandemic has laid bare the importance of non-pharmaceutical interventions in the containment of airborne infectious diseases. Social distancing and mask-wearing have been found to contain COVID-19 spreading across a number of observational studies, but a precise understanding of their combined effectiveness is lacking. An underdeveloped area of research entails the quantification of the specific role of each of these measures when they are differentially adopted by the population.

COVID-19 Modeling: High-Resolution Agent-Based Modeling of COVID-19 Spreading in a Small Town (Adv. Theory Simul. 3/2021).

Since 2020, COVID-19 has wreaked havoc across the planet, taking the lives of more than one million people. The uncertainty and novelty of the current conditions call for the development of theory and simulation tools that can support effective policy-making. In article number 2000277, Agnieszka Truszkowska, Maurizio Porfiri, and co-workers report a high-resolution, agent-based modeling platform to simulate the spreading of COVID-19 in the city of New Rochelle, NY-one of the first outbreaks registered in the United States.

High-Resolution Agent-Based Modeling of COVID-19 Spreading in a Small Town.

Amid the ongoing COVID-19 pandemic, public health authorities and the general population are striving to achieve a balance between safety and normalcy. Ever changing conditions call for the development of theory and simulation tools to finely describe multiple strata of society while supporting the evaluation of "what-if" scenarios. Particularly important is to assess the effectiveness of potential testing approaches and vaccination strategies.

Ultrasonic vocalization sex differences in 5-HT-R deficient mouse pups: Predictive phenotypes associated with later-life anxiety-like behaviors.

Anxiety disorders affect nearly twice as many women as men. However, little is known regarding sex-dependent developmental behavioral differences and whether there is an association with later life anxiety disorders. The present study assessed the developmental-behavioral milestones (DBMs) and their relationship with later life anxiety-like behaviors by comparing postnatal ultrasonic vocalizations (USVs) with open field (OF), elevated plus maze (EPM), and light/dark (LD) anxiety test outcomes using the serotonin 1A receptor knockout (KO) mouse model of anxiety.