Publications by authors named "Brandi A Ritter"
Article Synopsis
- Snakebite envenoming (SBE) causes over 500,000 deaths or serious injuries annually, and a phase II clinical trial was conducted to evaluate the safety and efficacy of varespladib methyl, an oral treatment, in patients bitten by venomous snakes.
- The trial, which was double-blind and placebo-controlled, enrolled patients in emergency departments in the USA and India, assessing changes in severity of snakebite symptoms using the Snakebite Severity Score (SSS) after treatment.
- Results indicated no significant difference in SSS improvement between the varespladib and placebo groups overall, but early treatment (within 5 hours of the bite) showed potential benefits in illness severity and recovery outcomes.
Background: Although the scientific results of recent tourniquet advances in first aid are well recorded, the process by which tourniquet use advances were made is not. The purpose of the present report is to distill historical aspects of this tourniquet story during the current wars in Afghanistan and Iraq to aid scientists, leaders, and clinicians in the process of development of future improvements in first aid.
Methods: The process of how developments of this tourniquet story happened recently is detailed chronologically and thematically in a ?who did what, when, where, why, and how? way.
Background: Tourniquet use recently became common in war, but knowledge gaps remain regarding analysis of recovered devices. The purpose of this study was to analyze tourniquets to identify opportunities for improved training.
Methods: We analyzed tourniquets recovered from deceased service members serving in support of recent combat operations by a team at Dover Air Force Base from 2010 to 2012.
Intraosseous vascular infusion (IO) is a recognized alternative to peripheral intravenous infusion when access is inadequate. The sternum and proximal tibia are the preferred sites. A review of 98 cases at autopsy revealed successful sternal IO placement in 78 cases (80%).
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