Impact of macular edema on visual acuity in uveitis.

Objective: To investigate the impact of cystoid macular edema (CME) on visual acuity in patients with uveitis.

Design: Cross-sectional study.

Participants: The data from 529 patients (842 eyes) with uveitis were analyzed.

Distinct cytokine and chemokine profiles in the aqueous of patients with uveitis and cystoid macular edema.

Purpose: To investigate the global cytokine and chemokine expression pattern in the aqueous humor of uveitis patients and relate them to clinical features.

Design: Cross-sectional study.

Methods: In 31 aqueous humor samples from uveitis patients, the concentration of mediators was measured by a multiplex immunoassay.

The pros and cons of intravitreal triamcinolone injections for uveitis and inflammatory cystoid macular edema.

Intravitreal triamcinolone acetonide (IVTA) injections are gaining in popularity and are regularly administered nowadays for various ocular diseases. This paper presents a literature review on the use, efficacy, and complications of IVTA application in non-infectious uveitis and inflammatory cystoid macular edema (CME). In addition, we describe the experiences of our own institute.

A randomized, masked, cross-over trial of lisinopril for inflammatory macular edema.

Purpose: To analyze the effect of angiotensin-converting enzyme (ACE) inhibitor lisinopril on inflammatory cystoid macular edema and visual acuity.

Design: Randomized, double-blind, placebo-controlled cross-over trial.

Methods: setting: Outpatient clinic of the Department of Ophthalmology at the University Medical Center of Utrecht.

Rapid progression of diabetic retinopathy in eyes with posterior uveitis.

Purpose: To report on two patients who developed rapid progression of asymmetric diabetic retinopathy (DRP) in eyes affected by posterior uveitis in contrast to their fellow eyes not affected by uveitis.

Design: Observational case report.

Methods: Two patients with diabetes mellitus (DM) and unilateral uveitis underwent repeated ophthalmologic examinations and fluorescein angiography.

The effect of non-steroidal anti-inflammatory drugs on inflammatory cystoid macular edema.

Purpose: To assess the role of systemic non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of inflammatory cystoid macular edema (iCME).

Design: Pilot study.

Methods: We included 66 patients with iCME and treated them with naproxen (2 x 250 mg daily; n = 28) or rofecoxib (1 x 25 mg daily; n = 38).

Trace microalbuminuria in inflammatory cystoid macular edema.

Purpose: To assess the role of cardiovascular morbidity, its risk factors, and microalbuminuria in the development of inflammatory cystoid macular edema (CME).

Design: A matched case-control study.

Methods: study population: We included 24 consecutive patients with uveitis and CME.

Birdshot chorioretinopathy: long-term manifestations and visual prognosis.

Purpose: To ascertain the clinical features and long-term visual prognosis of birdshot chorioretinopathy (BCR), and to identify patients at risk of visual loss.

Design: Retrospective noncomparative case series.

Participants: Fifty-five consecutive patients with HLA-A29-positive BCR who were identified in ophthalmology departments of the University Medical Center of Utrecht and The Eye Hospital Rotterdam, of whom 37 were observed for at least 5 years.