Publications by authors named "Bram Verstock"
Article Synopsis
- - The study investigates why recruitment rates in inflammatory bowel disease (IBD) trials are declining, focusing on screen failure (SF) proportions and their causes across phase 2 and 3 trials for ulcerative colitis (UC) and Crohn's disease (CD).
- - An analysis of 17 clinical trials revealed that 43% of UC patients and 53% of CD patients experienced SF, with key reasons being inability to meet specific clinical and endoscopic criteria, along with infections like Clostridium difficile.
- - The findings highlight that high SF rates, especially in CD trials, hinder patient recruitment, largely due to rigid and often unclear eligibility criteria.
Background: Autoimmune pancreatitis [AIP] is rarely associated with inflammatory bowel disease [IBD]. The long-term outcomes of AIP and IBD in patients with coexisting AIP-IBD and predictors of complicated AIP course have rarely been reported.
Methods: An ECCO COllaborative Network For Exceptionally Rare case reports project [ECCO-CONFER] collected cases of AIP diagnosed in patients with IBD.