Publications by authors named "Bram Ja Vermeulen"
Article Synopsis
- The γ-tubulin ring complex (γ-TuRC) serves as a template for assembling microtubules from α/β-tubulin, and its structure influences how microtubules form.
- Research on microtubules from Xenopus laevis reveals that the γ-TuRC is only partially closed at the minus end, leading to an asymmetric and misaligned microtubule structure.
- This unique configuration suggests that it affects the binding of microtubule-modulating factors and plays a crucial role in the regulation of microtubule nucleation during spindle assembly.
