Comment on "gemcitabine, PI3kinase-Akt pathway inhibition and radiation in human glioma cell lines" by M.S. Elnaggar et al..

The combination of gemcitabine, PI3K-Akt pathway inhibitors, and radiation in human glioma cell lines shows potential to enhance radiation sensitivity in aggressive brain tumors. Inhibiting the overactive PI3K-Akt pathway may increase tumor vulnerability to treatment. However, variability in responses among different glioma cell lines highlights the need for personalized approaches.

Artificial intelligence in neuroimaging: Opportunities and ethical challenges.

The integration of artificial intelligence (AI) into neuroimaging represents a transformative shift in the diagnosis and treatment of neurodegenerative diseases. AI algorithms, particularly deep learning models, have demonstrated remarkable capabilities in analyzing complex neuroimaging data, leading to enhanced diagnostic accuracy and personalized treatment strategies. This letter discusses the opportunities AI presents in neuroimaging, including improved disease detection, predictive modeling, and treatment planning.

Evaluation of the Phytochemical Screening of Methanolic Seed Extracts of Tribulus terrestris: An In Vitro Application of Anti-cancer, Anti-oxidant, and Anti-microbial Activities.

Background: , a plant known for its pharmacological properties, was investigated in this study for its potential anticancer effects against oral cancer cells. The study aimed to explore the phytochemical composition of seed extract and evaluate its cytotoxic, pro-apoptotic, antioxidant, anti-inflammatory, and antimicrobial activities.

Materials And Methods: Methanolic seed extracts of were obtained and subjected to phytochemical analysis to identify bioactive compounds.

Studies on In Vitro Antimicrobial, Anticancer, and Anti-oxidative Inflammatory Response of Methanolic Tuber Extracts Derived From Terminalia chebula.

Aim This study aims to investigate the antibacterial, antifungal, and phytochemical properties of methanolic tuber extracts from . Additionally, the study seeks to assess the in vitro anticancer effects of these extracts on an oral cancer cell line, as well as their antioxidant and anti-inflammatory activities. Materials and methods The research involves examining the antibacterial and antifungal properties of methanolic tuber extracts from .

Pharmacological Effect of Copper Oxide Nanoparticles of Leaf Extract and Application for its Antibacterial Properties.

Nanoparticles prepared from bio-reduction agents are of keen interest to researchers around the globe due to their ability to mitigate the harmful effects of chemicals. In this regard, the present study aims to synthesize copper oxide nanoparticles (CuO NPs). CuNPs show a characteristic absorption peak at 347 nm, while SEM reveals the spherical but agglomerated shape of CuNPs of the size within the range of 51.

Antimicrobial Activity and Biological Compatibility Study of Methanolic Crude Extract of (Flower).

is a little flowering tree or shrub that is indigenous to India and Sri Lanka. It is also known by the names Tanner's Cassia and Avarampoo. It is a member of the Fabaceae family and is popular for its therapeutic and beautifying effects.

Pharmacological Effect of Antioxidant Property and Green Synthesis of Silver Nanoparticles (AgNPs) Utilizing Antibacterial Application.

Background: Nonessential heavy metals pose a significant threat to human health due to their toxicity. Mercury, in particular, is identified as a hazardous metal. The study aims to detect mercury using colorimetric analysis with Murraya koenigii, emphasizing the eco-friendliness of the method.

One Step Rapid Sensitive Method for the Diagnosis of Hemolysin Gene of by Polymerase Chain Reaction.

is a Gram-negative bacterium that has been linked to serious illnesses in both humans and animals. The presence of hemolysin, a virulence factor, is critical in the development of -related illnesses. As a result, precise and timely detection of the hemolysin gene is critical for efficient diagnosis and prevention of many illnesses.

Phytochemical Analysis of Silver Nanoparticles of Leaf Extract and Evaluation for Its Antibacterial Property.

Nonessential heavy metals are toxic to human health. In this study, mercury, a hazardous metal, was detected by colorimetric analysis using . The eco-friendliness of this method was also emphasized.

Phytochemical Analysis of Silver Nanoparticles of and Evaluation for Its Antibacterial Property.

Nonessential heavy metals are toxic to human health. In this study, mercury, a hazardous metal, was detected by colorimetric analysis using . The eco-friendliness of this method was also emphasized.

Systematic Evaluation of Aegle marmelos-Derived Compounds: Potential Therapeutic Agents Against Inflammation and Oxidative Stress.

Aim This study aimed to evaluate the potential antioxidant and anti-inflammatory properties of active compounds through a multifaceted approach. The investigation encompasses molecular docking studies, computational pharmacokinetic predictions, and in vitro assessments, with a focus on understanding their physiochemical properties, pharmacokinetics, and molecular interactions. Materials and methods This study was conducted in the Research Department of Biochemistry, Saveetha Medical College & Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Tamilnadu, India.

In Vitro Antioxidant Activity of Green-Synthesized Zinc Oxide (ZnO) Nanoparticles Utilizing Extracts From Allium sativum.

Introduction: The primary objective of this study was to develop an environmentally friendly and efficient method for synthesizing zinc oxide (ZnO) nanoparticles (NPs), utilizing extracts from (garlic) plants, characterizing the synthesized ZnO NPs using various analytical techniques, and assessing their antibacterial and antioxidant properties.

Materials And Methods: The synthesis process involved utilizing extracts from garlic plants to create ZnO NPs. The NPs were subjected to comprehensive characterization through UV-visible (UV-vis) spectroscopy, Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and X-ray diffraction (XRD).