Publications by authors named "Brady P"

Article Synopsis
  • The study aimed to compare functional vision loss (FVL) between adults and children, focusing on how it manifests and the factors contributing to it.
  • A total of 27 studies involving 1,476 patients were analyzed; findings revealed similar rates of visual acuity loss but higher rates of visual field defects in adults.
  • The study highlighted different psychiatric and stress-related factors affecting adults and children, noted limitations in data consistency, and suggested the need for further research on treatment options and understanding FVL in different age groups.
View Article and Find Full Text PDF

Background: The objective of this study was to compare the accuracy of available tests for pyuria, including newer automated tests, and to examine the implications of requiring them for the diagnosis of urinary tract infections (UTIs).

Methods: We included children between 1 and 36 months of age undergoing bladder catheterization for suspected UTIs who presented to 1 of 3 pediatric centers. Using a positive urine culture result as the reference standard, we compared the sensitivity of 5 modalities for assessing pyuria at the cutoffs most often used clinically for detecting children with a positive culture result: leukocyte esterase on a dipstick, white blood cell (WBC) count on manual microscopy with and without using a hemocytometer, automated WBC enumeration using flow cytometry, and automated WBC enumeration using digital imaging with particle recognition.

View Article and Find Full Text PDF

Objective: To determine whether shopper-reported availability of foods from Minnesota food shelves and the importance of cultural foods/cooking items differed by demographic characteristics.

Methods: Cross-sectional survey of food pantry shoppers (n = 4,680) who visited more than or equal monthly with choice over food selection.

Results: Hispanic and Black shoppers had higher odds of reporting produce, eggs, and cooking items were always available than White shoppers (odds ratio [OR] > 1.

View Article and Find Full Text PDF

Objectives: To evaluate the prognostic value (total mortality + repeated hospitalization for heart failure (HF)) of ultrasound diagnostic methods in patients with acute decompensated HF (ADHF).

Methods: The subjects were patients with chronic HF, who were hospitalized for ADHF. Using ultrasound methods-lung ultrasound, ultrasound assessment of hepatic venous congestion as per the venous excess ultrasound (VExUS) protocol, and indirect elastometry-we assessed the number of B-lines, hepatic venous congestion, and liver density of the patients.

View Article and Find Full Text PDF

Our aim was to capture the perspectives of emergency food system (EFS) partners, providers, and rural older adults who receive emergency foods on their experiences throughout the COVID-19 pandemic. We conducted in-depth semi-structured qualitative interviews with partners in Minnesota's EFS ( = 9), rural emergency food providers ( = 5), and rural older adults who receive emergency food ( = 14) between July 2022 and February 2023. We used template analysis, a rapid qualitative method, to identify recurring perspectives across interviews.

View Article and Find Full Text PDF

Communication underlies every stage of the diagnostic process. The Dialog Study aims to characterize the pediatric diagnostic journey, focusing on communication as a source of resilience, in order to ultimately develop and test the efficacy of a structured patient-centered communication intervention in improving outpatient diagnostic safety. In this manuscript, we will describe protocols, data collection instruments, methods, analytic approaches, and theoretical frameworks to be used in to characterize the patient journey in the Dialog Study.

View Article and Find Full Text PDF

Food citizenship states individuals, organizations, and governments have responsibilities for their actions and policies around food. We conducted twenty semi-structured interviews with older adults as an exploratory study about perceived food-related responsibilities. The government and agribusiness were seen as responsible for food safety and how healthy foods are.

View Article and Find Full Text PDF

Introduction: During the COVID-19 pandemic, Supplemental Nutrition Assistance Program (SNAP) emergency allotments and emergency rent assistance provided support to low-income households. Rent burden, a form of housing insecurity, can severely limit household resources, which, in turn, affects health equity. We explored whether these policy interventions equitably supported households that were or were not experiencing rent burden.

View Article and Find Full Text PDF

Continuous pulse oximetry (cSpO) monitoring use outside established guidelines is common in children hospitalized with bronchiolitis. We analyzed clinicians' real-time rationale for continuous monitoring in stable children with bronchiolitis not requiring supplemental oxygen. Data for this study were collected as part a multicenter deimplementation trial for cSpO in children hospitalized with bronchiolitis.

View Article and Find Full Text PDF

Bone-modifying agents (BMAs) are integral to managing patients with advanced cancer. They improve quality of survival by reducing skeletal-related events, treating hypercalcaemia and chemotherapy-induced bone loss (Coleman in Clin Cancer Res 12: 6243s-6249s, 2006), (Coleman in Ann Oncol 31: 1650-1663, 2020). Two decades ago, medication-related osteonecrosis of the jaw (MRONJ) was first reported following BMA therapy (Marx in J Oral Maxillofac Surg 61: 1115-1117, 2003).

View Article and Find Full Text PDF

Background And Objectives: Variation in continuous cardiopulmonary monitor (cCPM) use across children's hospitals suggests preference-based use. We sought to understand how clinical providers make decisions to use cCPMs.

Methods: We conducted a qualitative study using semi-structed interviews with clinicians (nurses, respiratory therapists [RTs], and resident and attending physicians) from 2 hospital medicine units at a children's hospital.

View Article and Find Full Text PDF

Introduction: Physicians commonly recommend automatic primary care follow-up visits to children being discharged from the hospital. While automatic follow-up provides an opportunity to address postdischarge needs, the alternative is as-needed follow-up. With this strategy, families monitor their child's symptoms and decide if they need a follow-up visit in the days after discharge.

View Article and Find Full Text PDF

Background: Route of administration is an important component of antimicrobial stewardship. Early transition from intravenous to enteral antibiotics in hospitalized children is associated with fewer catheter-related adverse events, as well as decreased costs and length of stay. Our aim was to increase the percentage of enteral antibiotic doses for hospital medicine patients with uncomplicated common bacterial infections (community-acquired pneumonia, skin and soft tissue infection, urinary tract infection, neck infection) from 50% to 80% in 6 months.

View Article and Find Full Text PDF

Introduction: Prior studies have investigated the diagnostic potential of microRNA (miRNA) expression profiles for endometriosis. However, the vast majority of previous studies have only included adult women. Therefore, we sought to investigate differential expression of miRNAs among adolescents and young adults with endometriosis.

View Article and Find Full Text PDF
Article Synopsis
  • Current multimessenger searches for binary neutron star (BNS) and neutron star-black hole (NSBH) mergers are advancing with the gravitational wave observatories ALIGO, AdVirgo, and KAGRA during their fourth observing run (O4).
  • To enhance the search, the study utilized simulated binary populations and conducted a mock data challenge (MDC), optimizing the software used for real-time data analysis and alert generation.
  • The paper reports on the low-latency infrastructure performance, with a median alert time of approximately 29.5 seconds for full searches, and emphasizes the importance of early warnings for neutron star mergers with a new trigger system, aiming for responses about 3.1 seconds before mergers occur.
View Article and Find Full Text PDF

Purpose: To evaluate the efficacy and safety of hepatic artery interventions (HAI) versus extra-hepatic arterial interventions (EHAI) when managing clinically significant hepatic artery stenosis (HAS) after adult orthotopic liver transplantation.

Materials And Methods: A single-center retrospective cohort analysis was conducted on liver transplant patients who underwent intervention for clinically significant HAS from September 2012 to September 2021. The HAI treatment arm included hepatic artery angioplasty and/or stent placement while the EHAI treatment arm comprised of non-hepatic visceral artery embolization.

View Article and Find Full Text PDF

Introduction: The limited data indicate that pediatric medical errors in the outpatient setting, including at home, are common. This study is the first step of our to address medication errors and treatment delays among children with T1D in the outpatient setting. We aimed to identify failures and potential solutions associated with medication errors and treatment delays among outpatient children with T1D.

View Article and Find Full Text PDF

Objectives: We sought within an ambulatory safety study to understand if the Revised Safer Dx instrument may be helpful in identification of diagnostic missed opportunities in care of children with type 1 diabetes (T1D) and autism spectrum disorder (ASD).

Methods: We reviewed two months of emergency department (ED) encounters for all patients at our tertiary care site with T1D and a sample of such encounters for patients with ASD over a 15-month period, and their pre-visit communication methods to better understand opportunities to improve diagnosis. We applied the Revised Safer Dx instrument to each diagnostic journey.

View Article and Find Full Text PDF

Importance: Most children's hospitals have adopted weight-based high-flow nasal cannula (HFNC) bronchiolitis protocols for use outside of the intensive care unit (ICU) setting. Whether these protocols are achieving their goal of reducing bronchiolitis-related ICU admissions remains unknown.

Objective: To measure the association between hospital transition to weight-based non-ICU HFNC use and subsequent ICU admission.

View Article and Find Full Text PDF
Article Synopsis
  • Research in Pediatric Hospital Medicine is increasingly shifting from single-site to multisite studies to enhance the generalizability of findings across diverse populations.
  • Significant logistical challenges arise during this transition, including project management, regulatory approvals, and data agreements.
  • The overview includes lessons learned from the Pediatric Research in Inpatient Settings Network, helping hospitalist researchers successfully tackle their first multisite projects.
View Article and Find Full Text PDF
Article Synopsis
  • Children with congenital anomalies of the kidney and urinary tract (CAKUT) and neurogenic bladder (NGB) are more susceptible to treatment failure for urinary tract infections (UTIs) compared to those with normal anatomy, but research on this is limited.
  • A study analyzed 482 children aged 0 to 17 presenting with UTIs to emergency departments between 2017 and 2018 and found a 6% rate of treatment failure.
  • The duration of antibiotic treatment was similar for both those who experienced treatment failure and those who did not, highlighting the need for more extensive studies to explore the effects of bacteremia on treatment outcomes.
View Article and Find Full Text PDF

Background: Chronic kidney disease (CKD) is a common comorbid condition in patients undergoing transcatheter aortic valve replacement (TAVR). Reported outcome studies on the association of baseline CKD and mortality is currently limited.

Objectives: To determine the prevalence of chronic kidney disease in patients undergoing TAVR and analyse their overall procedural outcomes.

View Article and Find Full Text PDF