Publications by authors named "Brady B"

With recent technical advances, many cognitive and sensory tasks have been adapted for smartphone testing. This study aimed to assess the criterion validity of a subset of self-administered, open-source app-based cognitive and sensory tasks by comparing test performance to lab-based alternatives. An in-person baseline was completed by 43 participants (aged 21 to 82) from the larger Labs without Walls project (Brady et al.

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Background: Culture and its practice is a recognised, but not well understood factor, in Aboriginal health and wellbeing. Our study aimed to explore how health and wellbeing are phenomenologically connected to cultural practices, foods, medicines, languages, and Country, through the platform of 'on-Country' camps facilitated by Aboriginal cultural knowledge holders in NSW, Australia.

Methods: Our study is based on a collaboration between knowledge holders from freshwater and saltwater cultures, and Aboriginal and non-Aboriginal researchers.

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Background: Aboriginal and Torres Strait Islander peoples' have sustained their cultural practices for over 60,000 years which fundamentally impacts their health and wellbeing. Recent literature emphasizes cultural connection as a contributor to good public health, yet the mechanisms through which cultural engagement promotes health and wellbeing remain underexplored. This study investigates the health and wellbeing outcomes associated with Aboriginal peoples' participation in cultural camps in New South Wales (Australia), focusing on the role of cultural determinants of health.

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Unlabelled: Indigenous cultural health is an emerging field of research and reflects the unique connections Indigenous peoples have with their Country, culture, and knowledge systems. This narrative review explores the concept of cultural health focusing on the interplay between culture, health, and wellbeing within settler colonial contexts. The review is mostly focused on Australian research, despite its international scope.

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Background: U.S. policy intervention to increase methadone treatment accommodations during COVID did not result in national adoption of the new patient-centered treatment practices.

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Background: A service-focussed placement model involves an innovative partnership between service and education providers to a) address service delivery needs and b) facilitate students' competency development. Services are collaboratively redesigned such that students are positioned as collaborators in service delivery with their learning supported through evidence-informed educational design. This model was implemented in the hospital setting and was found to promote positive patient outcomes.

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Kidney disease and its comorbidities disproportionately affect older persons. Kidney disease modifying therapy is underutilized in older adults, as guidelines lack consensus on approaching diagnosis and treatment in older adults. This review aims to highlight the challenges presented by, and opportunities for, identifying and treating CKD in older adults.

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Objectives: Interpersonal relevancy appraisals are a dynamic and understudied aspect of human social cognition. Despite their importance, there are no existing measures. This study developed and validated a new measure of self-perceived interpersonal threat, opportunity, and invisibility appraisals among a life-course sample of adults.

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Background: Persistent high levels of knee pain after a total knee replacement have been estimated to affect 5%-10% of people and this is related to dissatisfaction with surgery, reduced function and reduced quality of life. This systematic review aims to evaluate the effectiveness of rehabilitation programs or strategies to reduce persistent pain and improve function and quality of life in people following a total knee replacement.

Methods: The systematic review was conducted following PRISMA guidelines with a search of relevant online databases up to 17 July 2024.

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Importance: The multifaceted nature of screen use has been largely overlooked in favor of a simplistic unidimensional measure of overall screen time when evaluating the benefits and risks of screen use to early childhood development.

Objective: To conduct a systematic review and meta-analysis to examine associations of screen use contexts in early childhood with cognitive and psychosocial outcomes.

Data Sources: PsycINFO, Embase, MEDLINE Ovid, ProQuest, CINAHL, Web of Science, and Scopus were searched from inception to December 31, 2023.

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Article Synopsis
  • Ischemic strokes disrupt mitochondrial function in brain endothelial cells, leading to long-term neurological issues.
  • A study found that using extracellular vesicles (EVs) from mouse brain endothelial cells (mBECs) showed better therapeutic effects in mouse models than those from human cells (hBECs).
  • mBEC-derived EVs enhanced ATP production and mitochondrial function while reducing brain damage and improving neurological outcomes in stroke-affected mice.
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Previous research suggests that individuals with mental health needs and chronic pain may be less likely to use mental health treatment compared with those with mental health needs only. Yet, few studies have investigated the existence of population-level differences in mental health treatment use. We analyzed data from the National Health Interview Survey (n = 31,997) to address this question.

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Article Synopsis
  • Researchers wanted to see how well people with type 2 diabetes stick to their medicine, focusing on oral semaglutide and a different type called DPP-4 inhibitors.
  • They looked at data from a huge database and checked how many days people kept taking their meds over a year.
  • The study found that people used both types of medicine about the same amount, but using oral semaglutide might mean you need fewer other medications to help with diabetes.
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The purpose of this review is to summarize essential biological, pharmaceutical, and clinical aspects in the field of topically applied medicines that may help scientists when trying to develop new topical medicines. After a brief history of topical drug delivery, a review of the structure and function of the skin and routes of drug absorption and their limitations is provided. The most prevalent diseases and current topical treatment approaches are then detailed, the organization of which reflects the key disease categories of autoimmune and inflammatory diseases, microbial infections, skin cancers, and genetic skin diseases.

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Introduction: Pain in Parkinson's disease (PD) is common but poorly understood, with most research to date taking a mechanistic approach. This mixed methods study takes a broader biopsychosocial approach to assess and describe contributors of pain and explore pain management and the relationship between pain and physical activity in people with PD (PwPD) and chronic pain.

Methods: A structured survey evaluated respondents' contributors of pain using standardized, self-report assessments of the following: pain, peripheral neuropathy, central nociplastic change, emotional dysregulation or pathology, and maladaptive cognitions.

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Purpose: The aim of this review was to assess the effectiveness of multidisciplinary, activity-based interventions on adults with chronic musculoskeletal or widespread pain who identify as ethnoculturally diverse (ECD) compared to adults belonging to the predominant culture of the host country.

Methods: Online databases Medline, CINAHL, AMED, Psych Info and PubMed were searched from the earliest date available until April 2023. The quality of the included studies were assessed against the Risk of Bias in Non Randomized Studies of Interventions (ROBINS-I).

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Objective: The study was to determine the prevalence of baseline risk factors for cardiovascular outcomes and cancer among commercially-insured patients with rheumatoid arthritis (RA) during their first dispensed treatment for either tumor necrosis factor inhibitors (TNFi) or JAK inhibitors (JAKi).

Methods: Patients with RA from August 16, 2019 to March 31, 2022 were identified in the Merative MarketScan Commercial and Medicare databases. The first date that a TNFi or JAKi was dispensed was the index date, and baseline risk factors were assessed among patients continuously eligible for 12 months before the index date.

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Objective: The objective of this study is to examine rural hospitals' status in implementing opioid stewardship program (OSP) elements and assess differences in implementation in emergency department (ED) and acute inpatient departments.

Design: Health administrator survey to identify the number and type of OSP elements that each hospital has implemented.

Setting: Arizona critical access hospitals (CAHs).

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Article Synopsis
  • The study aimed to enhance nursing clinical handovers through a tailored communication intervention, focusing on qualitative improvements in practice across multiple hospitals.
  • Data was collected through interviews, focus groups, and observations before and after the intervention, which involved redesigning handover practices based on feedback from various healthcare staff and patients.
  • Post-intervention results showed significant improvements in bedside handovers, with better patient engagement and information transfer, indicating that effective communication training and leadership can positively impact nursing practices.
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To survive cold winters, Florida manatees (Trichechus manatus latirostris) depend on artificial (i.e., power plants) and natural warm water sources such as springs and passive thermal basins.

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Article Synopsis
  • The study found that 30% of patients used prescribed opioids regularly before undergoing total knee or hip arthroplasty in Australia.
  • Despite this prevalence, the research showed no significant link between preoperative opioid use and the rates of complications or readmissions, nor did it affect the patients’ reported outcomes up to six months after surgery.
  • This suggests that while opioid use is common among these patients, it may not impact their recovery or overall surgical success as previously thought.
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Objectives: To explore the experiences of socio-culturally diverse community members attempting to manage their chronic pain and enact evidence-based management plans following an index Emergency Department (ED) visit.

Methods: A convergent parallel mixed-methods design with qualitative interviews and descriptive analysis was undertaken in two public hospitals in a multicultural region in Sydney, Australia. Consecutive adults were recruited from culturally and linguistically diverse (CALD: n = 45) or Australian-born (n = 45) backgrounds, who presented to the ED for a chronic neuromusculoskeletal pain condition.

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