Publications by authors named "Bradley Y-W Man"
Nucleic Acids Res
May 2011
Article Synopsis
- Transcription factors, like NF-κB, play critical roles in cellular processes and are linked to various diseases, making their detection important for early diagnosis and prevention.
- Current detection methods are often complicated and impractical, prompting the need for simpler alternatives.
- This study introduces a new label-free luminescent detection method for NF-κB activity using a ruthenium complex, demonstrating its effectiveness for screening potential inhibitors that could help in developing treatments for diseases related to transcription factor deregulation.
