A 60-year-old white man seen in consultation for "chronic zoster" presented with a 30-year history of persistent, painful cutaneous lesions on his right flank. His pain was episodic and exacerbated by physical touch and emotional stress. He denied lesion sensitivity to cold or heat.
View Article and Find Full Text PDFAdvances in transplantation technique and posttransplantation immunosuppression have resulted in continual improvements in survival and quality of life of transplant recipients. The improved quality of life afforded in the posttransplantation period allows patients to lead more active lifestyles, which often includes increased exposure to solar radiation. This growing population of active, immunosuppressed individuals is at marked risk, up to 65 times that of the general population, for the development of cutaneous neoplasms with associated morbidity and mortality.
View Article and Find Full Text PDFBilateral facial angiofibromas are common cutaneous manifestations of tuberous sclerosis, an autosomal-dominant disease characterized by hamartomas of multiple organs. Papules in patients with tuberous sclerosis typically appear between 4 and 10 years of age, becoming more extensive during puberty before stabilizing. We present a 28-year-old man with unilateral facial angiofibromas, which may represent a segmental form of tuberous sclerosis.
View Article and Find Full Text PDFBackground: Dermatofibromas are common benign cutaneous fibrohistiocytic neoplasms, whereas melanomas are potentially aggressive malignancies. Differentiating these two entities can occasionally be difficult.
Methods: We report the case of a 56-year-old female presenting with a firm pink papule on the left thigh.
Clin Transplant
December 2005
Background: Solid organ transplant recipients (OTRs) are a growing population at high risk for cutaneous neoplasms, resulting in significant post-transplant morbidity and mortality. Management of malignant and pre-malignant cutaneous lesions in transplant recipients is challenging, making prevention of such neoplasms paramount. The objectives of the present study are to review and analyze systemic strategies for chemoprevention of malignant and pre-malignant cutaneous neoplasms in OTRs.
View Article and Find Full Text PDFBackground: Solid organ transplant recipients have an increased incidence of multiple cutaneous neoplasms.
Objective: We hope to draw attention to the potential risk for organ transplant recipients to develop atypical fibroxanthomas.
Methods: A review of the patient's medical record was performed and summarized as a case report.
Solid organ transplant recipients are a growing population at increased risk for the development of cutaneous premalignant and malignant lesions, resulting in significant morbidity and mortality. Topical immunomodulators, in particular imiquimod, have shown efficacy in the management of multiple malignant, precancerous, and viral conditions. The ability to locally induce an immune response, presumably against tumor and viral antigens, and induce apoptosis makes topical immunomodulators a promising therapeutic option in organ transplant recipients.
View Article and Find Full Text PDFObjective: To evaluate and compare the efficacy of the Semont liberatory maneuver on "objective" benign paroxysmal positional vertigo (BPPV) defined as vertigo with geotropic nystagmus in Dix-Hallpike positioning versus "subjective" BPPV defined as vertigo without nystagmus in Dix-Hallpike positioning.
Study Design: Retrospective chart review.
Methods: One hundred sixty-two patients with positional vertigo during Dix- Hallpike positioning were identified.