Treatment of spider veins of the lower extremity with a novel 532 nm KTP laser.

Background And Objectives: This study investigated a novel, high-power, 532 nm frequency-doubled Nd:YAG, KTP laser with contact cooling for the treatment of spider veins of the lower extremities.

Study: Twenty female subjects with Fitzpatrick skin types I-III, were treated to 79 sites using the 532 nm wavelength of a dual-wavelength 532/1,064 nm laser (Excel V, Cutera, Brisbane, CA) with a 5 mm-diameter spot, fluences ranging from 13 to 15 J/cm(2) , and a pulse-duration of 40 milliseconds. Two treatments were performed 12 weeks apart.

Prospective multicenter clinical trial of a minimally invasive temperature-controlled bipolar fractional radiofrequency system for rhytid and laxity treatment.

Background: A minimally invasive fractional bipolar radiofrequency (FRF) was developed.

Objective: To evaluate safety and efficacy of FRF in reducing face and neck rhytides and laxity.

Materials And Methods: This prospective, open-label, multicenter clinical trial enrolled 100 subjects with mild to severe facial and neck rhytides and laxity at seven centers in a per-protocol analysis.

Elastometry and clinical results after bipolar radiofrequency treatment of skin.

Background: The healing process of a novel radiofrequency bipolar system was recently shown to produce a profound increase in collagen and elastin content.

Objective: To determine the relationship between subjective clinical improvement scores and changes in objective measures of mechanical skin properties.

Methods And Materials: Elastometry measurements were made at baseline and 3 months after treatment.

Blinded, randomized, quantitative grading comparison of minimally invasive, fractional radiofrequency and surgical face-lift to treat skin laxity.

Objectives: To quantify the improvements in laxity from the surgical face-lift and to perform a randomized, blinded comparison with the clinical effects of a novel, minimally invasive fractional radiofrequency (FRF) system.

Study Design: Randomized, blinded, comparative trial.

Patients: Fifteen sequential patients with facial skin laxity enrolled in the trial and completed FRF treatment and follow-up.

A predictive model of minimally invasive bipolar fractional radiofrequency skin treatment.

Background: A novel bipolar fractional radiofrequency (FRF) system with temperature feedback was recently developed for facial laxity and rhytid treatment. The study objective was to develop a model based on published in vivo human skin data that could be extrapolated to aid physicians in making future dosimetry choices under clinically relevant conditions.

Methods: A standard electrode pair designed for use with the FRF system was modeled using finite element analysis (FEA).

Pilot clinical study of a novel minimally invasive bipolar microneedle radiofrequency device.

Background And Objectives: Noninvasive bipolar and monopolar radiofrequency (RF) deep dermal heating devices have previously been described. A novel minimally invasive RF device employing a bipolar microneedle electrode system is introduced and its resultant thermal effects on human skin in vivo were characterized for the first time.

Study Design/materials And Methods: An investigational 35 W RF device was configured to operate in bipolar mode delivering energy directly within the dermis using 5 microneedle electrode pairs with real-time feedback of tissue temperature for treatment control.

Bipolar fractional radiofrequency treatment induces neoelastogenesis and neocollagenesis.

Background: We recently introduced Renesis, a novel minimally invasive radiofrequency (RF) device, for the treatment of human skin. The wound healing response post-fractional RF (FRF) treatment was examined in human subjects.

Study Design: The FRF system delivered RF energy directly within the dermis via 5 micro-needle electrode pairs.