Publications by authors named "Bradley Presson"

Article Synopsis
  • - Stereotactic ablative body radiation (SABR) shows promise for treating early-stage non-small cell lung cancer (NSCLC), with 83% of patients remaining alive without tumor progression at a median follow-up of 40 months.
  • - The study examined the immune and pathological effects of SABR by analyzing blood and tumor biopsies from six patients before and after treatment, focusing on immune-cell populations and T-cell receptor changes.
  • - While early post-SABR biopsies revealed viable tumors and maintained immune-cell populations, a subset of patients exhibited a temporary increase in neoantigen-specific T-cells after treatment, suggesting that SABR can provoke a delayed immune response.
View Article and Find Full Text PDF

Heterotopic ossification (HO) is a pathologic process characterized by the formation of bone tissue in extraskeletal locations. The hip is a common location of HO, especially as a complication of arthroplasty. Here, we devise a first-of-its-kind mouse model of post-surgical hip HO and validate expected cell sources of HO using several HO progenitor cell reporter lines.

View Article and Find Full Text PDF