Working from home in medicine during coronavirus: What equipment do you need to get started and what can you do to help from home?

The COVID-19 pandemic looks set to significantly change how we practice medicine. It is vital that the vulnerable and immunocompromised members of our workforce are protected, which may mean that they do not go into clinical areas. While the medical field has been slower than many professional areas to catch on to working from home, many trusts are already moving towards telephone or video outpatient appointments during COVID-19.

Correlation Between Ankle-Dorsiflexion and Hip-Flexion Range of Motion and the Functional Movement Screen Hurdle-Step Score.

Context: Functional movement screening (FMS) has been gaining popularity in the fields of sports medicine and performance. Currently, limited research has examined whether FMS screening that identifies low FMS scores is attributed primarily to limits in range of motion (ROM).

Objective: To compare scores from the FMS hurdle-step movement with ROM measurements for ankle dorsiflexion and hip flexion (HF).

Effects of Core-Musculature Fatigue on Maximal Shoulder Strength.

Context: Core stability has been shown to affect lower-extremity motion, but activation of the core has also been observed just before movements of the upper extremity. However, there is limited evidence regarding the effects that core musculature has on upper-extremity strength.

Objective: To determine the effects of core fatigue on maximal shoulder strength.

Lack of neuromuscular origins of adaptation after a long-term stretching program.

Context: Static stretching is commonly used during the treatment and rehabilitation of orthopedic injuries to increase joint range of motion (ROM) and muscle flexibility. Understanding the physiological adaptations that occur in the neuromuscular system as a result of long-term stretching may provide insight into the mechanisms responsible for changes in flexibility.

Objective: To examine possible neurological origins and adaptations in the Ia-reflex pathway that allow for increases in flexibility in ankle ROM, by evaluating the reduction in the synaptic transmission of Ia afferents to the motoneuron pool.

Intersession reliability of Hoffmann reflex gain and presynaptic inhibition in the human soleus muscle.

Unlabelled: Hayes BT, Hicks-Little CA, Harter RA, Widrick JJ, Hoffman MA. Intersession reliability of Hoffmann reflex gain and presynaptic inhibition in the human soleus muscle.

Objective: To determine the day-to-day reliability of Hoffmann reflex (H-reflex) gain and presynaptic inhibition of spinal reflexes in the human soleus muscle.

The interrelationships among sex hormone concentrations, motoneuron excitability, and anterior tibial displacement in women and men.

Context: Sex hormone fluctuations have been implicated as a contributing factor to the high rates of noncontact injury to the anterior cruciate ligament in females.

Objective: To determine the strength of the relationships among variables of sex hormone concentrations, motoneuron excitability, and anterior tibial displacement (ATD) in women and men and to determine if these relationships differ between the sexes.

Design: Cohort study.

Three-MHz Ultrasound Heats Deeper Into the Tissues Than Originally Theorized.

OBJECTIVE: To measure muscle temperature of ultrasound at 1-MHz and 3-MHz frequencies at a depth of 2.5 cm and to compare treatment durations for vigorous heating (increase of 4 degrees C) and for heating to 40 degrees C. DESIGN AND SETTING: A counterbalanced, repeated-measures design with 1 fixed, independent variable, 1.

Metabolic functionalization of recombinant glycoproteins.

Glycoproteins are essential for cellular communication and are the most rapidly growing class of therapeutic agents. Chemical modification of glycoproteins has been employed to improve their in vivo efficacy or to label them for detection. Methods for the controlled derivatization of glycoproteins are presently limited by the repertoire of natural amino acid side chain and carbohydrate functionalities.

Dynamic interplay between O-glycosylation and O-phosphorylation of nucleocytoplasmic proteins: alternative glycosylation/phosphorylation of THR-58, a known mutational hot spot of c-Myc in lymphomas, is regulated by mitogens.

Previously, we reported that c-Myc is glycosylated by O-linked N-acetylglucosamine at Thr-58, a known phosphorylation site and a mutational hot spot in lymphomas. In this paper, we describe the production and characterization of two Thr-58 site-specific antibodies and use them to examine the modification of Thr-58 in living cells. One antibody specifically reacts with the Thr-58-glycosylated form of c-Myc, and the other reacts only with unmodified Thr-58 in c-Myc.