Publications by authors named "Bradley Fuhrman"
Objectives: The objectives of this review are to discuss the mechanisms by which respiration impacts cardiovascular function and vice versa, with an emphasis on the impact of these interactions in pediatric cardiac critical care.
Data Source: A search of MEDLINE was conducted using PubMed.
Conclusions: In the presence of underlying cardiac and respiratory disease, the interplay between these two systems is significant and plays a pivotal role in the pathophysiology of acute and chronic phases of a wide spectrum of diseases.
Objective: To evaluate the independent and combined effects of high-frequency oscillatory ventilation (HFOV) and partial liquid ventilation (PLV) on gas exchange, pulmonary histopathology, inflammation, and oxidative tissue damage in an animal model of acute lung injury.
Design: Prospective, randomized animal study.
Setting: Research laboratory of a health sciences university.
Objective: To evaluate the effect of low-bias flow oscillation (LBFO) with partial liquid ventilation (PLV) on perfluorochemical evaporation, histopathology, and oxidative tissue damage in an animal model of acute lung injury.
Design: Prospective, randomized animal study.
Setting: Research laboratory of a health sciences university.
Low bias flow oscillation with heliox in oleic acid-induced lung injury.
Pediatr Crit Care Med
January 2005
Objective: To evaluate Co(2) clearance in oleic acid-induced lung injury in rabbits receiving high-frequency oscillatory ventilation with helium-oxygen mixtures through a low bias flow oscillation system designed to conserve expensive gases.
Design: A prospective, controlled, interventional, in vivo animal laboratory study.
Setting: Research laboratory of a health sciences university.
Objective: To examine whether perfluorooctyl bromide (perflubron) is capable of protecting biological and nonbiological systems against oxidative damage through a mechanism independent of its known anti-inflammatory property.
Design: A controlled, in vitro laboratory study.
Setting: Research laboratory of a health sciences university.
Objectives: To evaluate carbon dioxide clearance in normal rabbits during high-frequency oscillatory ventilation with helium-oxygen mixtures by using a low bias flow oscillation (LBFO) system designed to conserve expensive gas.
Design: A prospective, paired-controlled, interventional, in vivo animal laboratory study.
Setting: Animal laboratory of a health science university.