Publications by authors named "Bradley C Saul"

Background: The 2013 ACC/AHA cholesterol treatment guidelines removed the recommendation to treat adults at risk of cardiovascular disease to goal levels of low-density lipoprotein cholesterol (LDL-C). We anticipated that the frequency of LDL-C testing in clinical practice would decline as a result. To test this hypothesis, we evaluated the frequency of LDL-C testing before and after the guideline release.

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Article Synopsis
  • M-estimation methods are useful for point estimation and making inferences in statistics.
  • The paper introduces an R package that helps users find roots and calculate empirical sandwich variance using their own unbiased estimating equations.
  • It also offers tools for correcting variances in various sampling scenarios and features a website with detailed tutorials.
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The United States Environmental Protection Agency considers nutrient pollution in stream ecosystems one of the U.S.' most pressing environmental challenges.

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Background: Evidence suggests that fasting, during which only water is consumed, results in potentially health promoting physiological effects. However, peer-reviewed research assessing the safety of water-only fasting is lacking. To address this, we conducted a chart review to describe adverse events (AEs) that occurred during medically supervised, water-only fasting.

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Article Synopsis
  • * Inverse probability weighted (IPW) estimators are typically used for estimating causal effects from observational data, but new methods have been developed to account for interference.
  • * The paper introduces an R package that computes IPW causal effect estimates considering interference, with applications demonstrated in political science and infectious disease studies.
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