Publications by authors named "Bradford S Goodwin"

Zebrafish (Danio rerio) are a popular vertebrate model in biomedical research, but information describing the effects of environmental enrichment on fertility and fecundity of zebrafish is sparse. In the current study, 18 breeding pairs were placed in divided 1.5-L breeding tanks containing 1 of 3 enrichment conditions: plastic grass (n = 6), plastic leaves (n = 6), or no enrichment (n = 6, control).

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Tail-tip biopsy for genotyping of genetically modified mice older than 21 d typically is performed by using isoflurane anesthesia. Isoflurane-induced changes in behavior and metabolism can result in unexpected complications and death. We investigated whether cryoanalgesia by using ethylene chloride spray would be an effective local anesthetic for tail-tip biopsies in mice.

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The rat spinal-cord-injury (SCI) model is widely used to study the pathologic mechanisms that contribute to sensory and motor dysfunction in humans. This model is thought to mimic many of the negative outcomes experienced by humans after spinal contusion injury. We theorized that manual bladder expression contributed to the kidney and bladder lesions reported in previous studies using the rat SCI model.

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Article Synopsis
  • Prostate cancer is the most common cancer and the second leading cause of cancer death in US men; this study explores using nanoparticles for photothermal treatment in canine prostate to mimic tumor treatment.
  • Canine prostates were surgically exposed, injected with nanoshells, and treated with a near-infrared laser, allowing researchers to evaluate the effectiveness and safety of the method through histopathological analysis post-euthanasia.
  • Results indicated that nanoparticles remained effective for 4 hours, and a specific laser dose could create controlled lesions with minimal damage to surrounding tissues, suggesting a potential for a precise and minimally invasive treatment for prostate cancer.
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The goal of this article is to present lessons learned from the devastating effects of two specific natural disasters in Texas: Tropical Storm Allison, which flooded Houston in June 2001, and Hurricane Ike, which caused severe damage in Galveston in September 2008. When a disaster is predictable, good predisaster planning can help to save animals lives. However, as disasters are usually not predictable and tend not to follow a script, that plan needs to be easily adaptable and flexible.

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