Publications by authors named "Bradford D Wilson"
Admixture Mapping Links RACGAP1 Regulation to Prostate Cancer in African Americans.
Cancer Genomics Proteomics
October 2018
Article Synopsis
- - Prostate cancer (PCa) is the most common cancer in men in the US, with African American men experiencing higher rates of incidence and mortality compared to European American men.
- - The study examined the association between specific haplotypes from five single nucleotide polymorphisms (SNPs) and PCa using a case-control approach, revealing significant links to certain haplotypes like "GTCCC," "ATTCT," and "ACCCC."
- - The findings suggest that the disruption of a specific protein related to cell signaling (RACGAP1) might play a role in the development of PCa in African American men.