On the feasibility of life-saving locomotive bumpers.

Motivated by the thousands of pedestrians killed each year in train impacts, this paper investigates the life-saving capability of four high-level locomotive bumper concepts. The head motions produced by the four concepts are modeled as one or two square acceleration pulses and are analyzed using the Head Injury Criterion (HIC). Surprisingly, the analyses show that all four concepts can achieve HIC values of less than 200 for an impact with a locomotive traveling at 100 km/h.

Lower Bounds on the Frequency Estimation Error in Magnetically Coupled MEMS Resonant Sensors.

MEMS inductor-capacitor (LC) resonant pressure sensors have revolutionized the treatment of abdominal aortic aneurysms. In contrast to electrostatically driven MEMS resonators, these magnetically coupled devices are wireless so that they can be permanently implanted in the body and can communicate to an external coil via pressure-induced frequency modulation. Motivated by the importance of these sensors in this and other applications, this paper develops relationships among sensor design variables, system noise levels, and overall system performance.

Safety-enhanced optimal control of turbodynamic blood pumps.

A safety-enhanced optimal (SEO) control algorithm for turbodynamic blood pump is proposed. Analysis of in vivo animal experimental data reveals that two new control indices-the gradient of pulsatility of pump pressure head with respect to pump speed and the gradient of minimum pump flow-have their peak within a proximity to the suction point but not at the exact suction point. They were also verified to satisfy the requirement of cost function for the extremum seeking control (ESC).

Experimental verification of the feasibility of the cardiovascular impedance simulator.

Mock circulatory systems (MCS) are often used for the development of cardiovascular devices and for the study of the dynamics of blood flow through the cardiovascular system. However, conventional MCS suffer from the repeatability, flexibility, and precision problems because they are typically built up with passive and linear fluidic elements such as compliance chamber, manual valve, and tube. To solve these limitations, we have developed an impedance simulator, comprised of a feedback-controlled positive displacement pump that is capable of generating analogous dynamic characteristics as the conventional fluidic elements would generate, thereby replacing the conventional passive fluidic elements that often cause problems.

Thermal Analysis of the PediaFlow pediatric ventricular assist device.

Accurate modeling of heat dissipation in pediatric intracorporeal devices is crucial in avoiding tissue and blood thermotrauma. Thermal models of new Maglev ventricular assist device (VAD) concepts for the PediaFlow VAD are developed by incorporating empirical heat transfer equations with thermal finite element analysis (FEA). The models assume three main sources of waste heat generation: copper motor windings, active magnetic thrust bearing windings, and eddy currents generated within the titanium housing due to the two-pole motor.