Publications by authors named "Brad D Riley"
Article Synopsis
- Intravenous lipid emulsion has been proposed as a potential antidote for toxic drug overdoses based on the "lipid sink" theory, which suggests it can help sequester lipophilic drugs in the bloodstream.
- The study analyzed 134 cases from a toxicology registry to see if the survival rate after lipid therapy was related to the lipophilicity of the intoxicants involved.
- Results showed that 80.6% of patients survived, but there was no significant link between the intoxicant's lipophilicity and survival; however, systolic blood pressure improved for both groups after treatment.
The Toxicology Investigators Consortium (ToxIC) Registry was established by the American College of Medical Toxicology (ACMT) in 2010. The Registry collects data from participating sites with the agreement that all bedside medical toxicology consultation will be entered. The objective of this ninth annual report is to summarize the Registry's 2018 data and activity with its additional 7043 cases.
View Article and Find Full Text PDFMany poisoned patients may only require a period of observation after their exposure. There are limited data describing the use of observation units for managing poisoned adult and pediatric patients. We performed a retrospective review of all patients reported to the ToxIC Case Registry between January 1, 2012 and December 31, 2013.
View Article and Find Full Text PDFBackground: Because the prevalence of type 2 diabetes increases annually, there has been an increase in pediatric exposures to sulfonylureas. These medications are associated with delayed and often prolonged hypoglycemia. As such, most authorities but not all recommend admission for all pediatric patients with an accidental sulfonylurea ingestion.
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