Esketamine has promising anti-inflammatory effects in orthopedic surgery and plays a protective role in postoperative cognitive function and pain management.

Objective: To investigate the effects of subanesthetic doses of esketamine on serum inflammatory cytokine levels and its impact on postoperative cognition and pain in patients undergoing elective orthopedic surgery.

Methods: From November 2023 to March 2024, patients scheduled for elective orthopedic surgery were randomly divided into an observation group or a control group, with 100 patients in each group (ChiCTR2300079156). The observation group received an intravenous injection of 0.

Urodynamic characteristics of awake rats under retrained versus freely moving condition: Using a novel model.

Urodynamic investigation in conscious rats is widely employed to explore functional bladder disorders of various etiologies and pathogeneses. Rats can be placed in restraining cages or wide cabinets where they are allowed to move freely during cystometry. However, the requirements of special devices hampered the application of urodynamic test in freely moving rats, and whether the restraint has any effects on urodynamic parameters in conscious rats remains obscure.

Sexual Practices, Fertility Intentions, and Awareness to Prevent Mother-to-Child Transmission of HIV Among Infected Pregnant Women at the Yaounde Central Hospital.

Introduction: The sexual and reproductive health of people living with HIV is fundamental for their well-being. Antiretroviral therapy and reproductive technologies have significantly improved quality of life of people living with HIV in developed countries. In sub-Saharan Africa, the epicenter of HIV, the sexual practices and fertility of women infected with HIV have been understudied.