Publications by authors named "Bozhen Ji"
Article Synopsis
- Preimplantation embryos experience essential biological processes like epigenetic reprogramming and lineage differentiation, crucial for reproductive success.
- Ubiquitin-specific protease 7 (USP7) is a key deubiquitinase whose specific role in embryo development is still unclear.
- Silencing USP7 in mouse embryos reduced blastocyst formation and quality, disrupted normal lineage differentiation, and affected the expression of important genes, indicating its vital role in the transition from morula to blastocyst and in regulating epigenetic modifications.
