Publications by authors named "Boyu Zhang"

Understanding and predicting human cooperative behaviour and belief dynamics remains a major challenge both from the scientific and practical perspectives. Because of the complexity and multiplicity of material, social and cognitive factors involved, both empirical and theoretical work tends to focus only on some snippets of the puzzle. Recently, a mathematical theory has been proposed that integrates material, social and cognitive aspects of behaviour and beliefs dynamics to explain how people make decisions in social dilemmas within heterogeneous groups.

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The significance of metastatic lymph nodes in tumor diagnosis and prognosis is self-evident. With the deepening of research on the lymphatic system and the advancement of imaging technology, an increasing number of near-infrared fluorescent probes targeting tumor metastatic lymph nodes have been developed. These probes can identify tumors while further detecting lymph nodes (LNs), showcasing great potential in image-guided surgery.

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Colorectal cancer remains a significant health threat, with its incidence continuously rising, underscoring the urgent need for the development of new therapeutic agents. In our previous research, we identified 7A, a derivative of Neratinib, as having pronounced antitumor activity. However, its specific effects and mechanisms in colorectal cancer have not been thoroughly investigated.

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The excessive emission and continuous accumulation of CO have precipitated serious social and environmental issues. However, CO can also serve as an abundant, inexpensive, and non-toxic renewable C carbon source for synthetic reactions. To achieve carbon neutrality and recycling, it is crucial to convert CO into value-added products through chemical pathways.

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Observation and understanding of fine-structure splitting of bright excitons in lead halide perovskite quantum dots (QDs) are crucial to their emerging applications in quantum light sources and exciton coherence manipulation. Recent studies demonstrate that ensemble-level polarization-resolved transient absorption spectroscopy can reveal the quantum beats arising from the coherence between two fine-structure levels. Here we report the observation of an extra fine-structure quantum coherence hidden in previous studies by using cryo-magnetic quantum beat spectroscopy.

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Drought is a global issue that has increasingly garnered worldwide attention. Glucosinolates (GSLs) are significant sulfur-containing compounds in cruciferous plants such as pakchoi (Brassica rapa L. ssp.

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: N-methyladenosine (mA), is the most common modification found in mRNA and lncRNA in higher organisms and plays an important role in physiology and pathology. However, its role in pan-cancer has not been explored. : A total of 31 mA modification regulators, including 12 writers, 2 erasers, and 17 readers are identified in the current study.

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Background: von Hippel-Lindau () harbors the highest mutational frequency in clear cell renal cell carcinoma (ccRCC). Although mutational subtypes exert diverse impacts on the functionality of the VHL protein, the clinical significance of mutational heterogeneity remains largely obscure.

Methods: This study included a total of 1331 patients with ccRCC from localized data sets, including our localized Zhongshan Hospital (ZSHS) cohort (n=1270) and Zhongshan immune checkpoint blockade cohort (n=61), as well as 525 patients with ccRCC from two publicly available data sets with matched clinical annotation and multidimensional data.

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Herein, we fabricated a low-melting-point Zr-16Ti-6Cu-8Ni-6Co eutectic filler based on a Zr-Ti-Cu-Ni filler to achieve effective joining of a Ti6Al4V (TC4) titanium alloy. The temperature at which the brittle intermetallic compound (IMC) layer in the seam completely disappeared was reduced from 920 °C to 900 °C, which broadened the temperature range of the Zr-based filler, brazing the TC4 without a brittle IMC layer. The shear strength of the Zr-16Ti-6Cu-8Ni-6Co brazed joint increased by 113% more than that of the Zr-16Ti-9Cu-11Ni brazed joint at 900 °C.

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Article Synopsis
  • Herpetospermum pedunculosum (HP), a traditional Tibetan herb, has shown potential in modern studies for treating liver damage, specifically in alleviating nonalcoholic fatty liver disease (NAFLD) through its lignan-rich extract (EAHP).
  • In an experiment using a mouse model of NAFLD, researchers evaluated EAHP's effects, finding significant improvements in liver health indicators, such as reduced liver size and liver damage markers in the serum, as well as better lipid metabolism.
  • Chemical analysis identified 36 compounds in EAHP, and further research indicated it regulates lipid abnormalities and inflammatory responses, showing promise for therapeutic use in liver-related diseases.
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Background: This study aims to investigate the morphological characteristics of the distal humerus in healthy adults from northern China using computed tomography and three-dimensional reconstruction techniques and compared whether there were diferences in morphology among populations from diferent geographical regions.

Methods: The CT data of 80 patients were imported into Mimics software for three-dimensional reconstruction and measurement. The differences in distal humeral morphological parameters between different genders and sides were compared, and the correlation between the parameters was explored.

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  • This study evaluated if seizure patterns seen in previous research were also detectable using wristband data combined with AI technology and patient self-reports for tonic-clonic seizures (TCS).
  • Over 137,000 TCS occurrences from over 3,000 patients were analyzed, revealing consistent monthly frequency distributions and various seizure cycles like daily and weekly patterns.
  • The findings suggest that wearable devices effectively track TCS occurrences non-invasively and over the long term, but highlight the need for better patient engagement with alerts and validation of detection methods.
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Background: Although decompression surgery is the optimal treatment for patients with severe degenerative cervical myelopathy (DCM), some individuals experience no improvement or even a decline in neurological function after surgery, with spinal cord ischemia-reperfusion injury (SCII) identified as the primary cause. Spinal cord compression results in local ischemia and blood perfusion following decompression is fundamental to SCII. However, owing to inadequate perioperative blood flow monitoring, direct evidence regarding the occurrence of SCII after decompression is lacking.

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Liquid-liquid or gas-liquid interfaces are ubiquitous in nature and in industrial production. Understanding the unique effects arising from the asymmetric interfaces and controlling the catalytic reactions are frontiers of physical chemistry. However, our understanding of the reactivity and selectivity at the interfaces remains scant.

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The ability to manufacture 3D metallic architectures with microscale resolution is greatly pursued because of their diverse applications in microelectromechanical systems (MEMS) including microelectronics, mechanical metamaterials, and biomedical devices. However, the well-developed photolithography and emerging metal additive manufacturing technologies have limited abilities in manufacturing micro-scaled metallic structures with freeform 3D geometries. Here, for the first time, the high-fidelity fabrication of arbitrary metallic motifs with sub-10 µm resolution is achieved by employing an embedded-writing embedded-sintering (EWES) process.

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In order to address the issues of excessive brittle intermetallic compounds (IMC) formation in the TC4 brazed joints, two types of novel Ti-Zr-Cu-Ni-Sn amorphous braze fillers were designed. The microstructure and shear strength of the TC4/Ti-Zr-Ni-Cu-Sn/TC4 brazed joints were studied by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffractometer (XRD) and electronic universal materials testing machine. The results show that the optimized TiZrNiCuSn braze filler whose chemical composition is closer to the eutectic point possesses a lower melting point compared with the equiatomic TiZrNiCuSn.

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Exposure to fine particulate matter (PM) in the ambient environment augments susceptibility to respiratory ailments. Circular RNAs, a distinctive subclass of endogenous non-coding RNAs, have been acknowledged as pivotal regulators of pathological conditions. Ferroptosis, an innovative iron-dependent form of cellular demise, has emerged as a consequential participant in numerous maladies.

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Nitrogen-doped biochar (NBC) is a green material for remediating heavy metal pollution, but it undergoes aging under natural conditions, affecting its interaction with heavy metals. The preparation conditions of NBC were optimized using response surface methodology (RSM), and NBC was subjected to five different aging treatments to analyze the removal efficiency of Cd(II) and soil remediation capability before and after aging. The results indicated that NBC achieved optimal performance with a mass ratio of 5:2.

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Cell dielectric property measurement holds significant potential for application in cell detection and diagnosis due to its label-free and noninvasive nature. In this study, we developed a biosensor designed to measure the permittivity of liquid samples, particularly cell suspensions at the nanoliter scale, utilizing microwave and millimeter wave coplanar waveguides in conjunction with a microchannel. This biosensor facilitates the measurement of scattering parameters within a frequency domain ranging from 1 GHz to 110 GHz.

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Depression, projected to be the predominant contributor to the global disease burden, is a complex condition with diverse symptoms including mood disturbances and cognitive impairments. Traditional treatments such as medication and psychotherapy often fall short, prompting the pursuit of alternative interventions. Recent research has highlighted the significant role of gut microbiota in mental health, influencing emotional and neural regulation.

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Wound healing in diabetic patients is frequently hampered. Adipose-derived stem cell exosomes (ADSC-eoxs), serving as a crucial mode of intercellular communication, exhibit promising therapeutic roles in facilitating wound healing. This review aims to comprehensively outline the molecular mechanisms through which ADSC-eoxs enhance diabetic wound healing.

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Aims: To investigate the association of the genetic predisposition of specific gut microbiotas with the clinical outcome of ischemic stroke.

Methods: We leveraged publicly available genome-wide association study (GWAS) data to perform Mendelian randomization (MR) analysis. The gut microbiota-related GWAS data from 18,340 individuals from the international consortium MiBioGen was used.

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