Publications by authors named "Boyu Lyu"
Article Synopsis
- * The study shows that a protein called Drp1 is essential for mitochondrial fission, which helps maintain the structure and organization of astrocytes during postnatal brain development.
- * Loss of Drp1 leads to abnormal astrocyte shapes and increased reactivity, along with a decrease in a crucial protein (Connexin 43) that affects astrocyte communication, highlighting the importance of mitochondria in brain health.
Motivation: Synapses are essential to neural signal transmission. Therefore, quantification of synapses and related neurites from images is vital to gain insights into the underlying pathways of brain functionality and diseases. Despite the wide availability of synaptic punctum imaging data, several issues are impeding satisfactory quantification of these structures by current tools.
View Article and Find Full Text PDFThe benzylisoquinoline alkaloids (BIAs) are an important group of secondary metabolites from higher plants and have been reported to show significant biological activities. The production of BIAs through synthetic biology approaches provides a higher-yielding strategy than traditional synthetic methods or isolation from plant material. However, the reconstruction of BIA pathways in microorganisms by combining heterologous enzymes can also give access to BIAs through cascade reactions.
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